Protein Alignment CG31549 and HSD17B14

DIOPT Version :9

• Sequence 1: NP_001262292.1
• Gene: CG31549 / 40689
• FlyBaseID: FBgn0051549
• Length: 257
• Species: Drosophila melanogaster
• Sequence 2: NP_057330.2
• Gene: HSD17B14 / 51171
• HGNCID: 23238
• Length: 270
• Species: Homo sapiens
• Alignment Length: 267
• Identity: 92/267 - (34%)
• Similarity: 130/267 - (48%)
• Gaps: 45/267 - (16%)

  Fly     4 FKDKVIIVTGASSGIGASAAVHLAKLGGLLVIVGRNEEKLKETADNIVAAGGATPLELQ------ 62
            :..||::|||...||||.........|..:||..::|           :.|.|...||.
Human     7 YAGKVVVVTGGGRGIGAGIVRAFVNSGARVVICDKDE-----------SGGRALEQELPGAVFIL 60

  Fly    63 ADMTKEAEVQQIVGATLAKHGRIDVLVNNAGILETGS-IEATSLEQFDRLMNTNVRSLYQLTMLA 126
            .|:|:|.:|:.:|..|:.:.||:|.:|||||...... .|.||.:.|.:|:..|:...|.||.||
Human    61 CDVTQEDDVKTLVSETIRRFGRLDCVVNNAGHHPPPQRPEETSAQGFRQLLELNLLGTYTLTKLA 125

  Fly   127 TPELVKTKGNIVNVSSVCGLRAFPGVLAYNVSKAAVDQFTACIALELAPKGVRVNAVNPGVIVTD 191
            .|.|.|::||::|:||:.|.......:.|..:|.||...|..:||:.:|.|||||.::||.|.|.
Human   126 LPYLRKSQGNVINISSLVGAIGQAQAVPYVATKGAVTAMTKALALDESPYGVRVNCISPGNIWTP 190

  Fly   192 IHK-------------RGGMDEETYAKFLEHCKITHALGRPGDVKEVAAAIAFLASDQASFTTGI 243
            :.:             |.||             :...|||.|...||.||..|||| :|:|.|||
Human   191 LWEELAALMPDPRATIREGM-------------LAQPLGRMGQPAEVGAAAVFLAS-EANFCTGI 241

  Fly   244 SLPVDGG 250
            .|.|.||
Human   242 ELLVTGG 248

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG31549	NP_001262292.1	NADB_Rossmann	4..254	CDD:304358	92/267 (34%)
		fabG	4..251	CDD:235975	92/267 (34%)
HSD17B14	NP_057330.2	RDH_SDR_c	1..256	CDD:187638	92/267 (34%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	128	1.000	Domainoid score	I5306
eggNOG	1	0.900	-	-		E2759_KOG0725
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	139	1.000	Inparanoid score	I4508
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D487970at33208
OrthoFinder	1	1.000	-	-		FOG0000019
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X68
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	6	5.960