DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG31549 and Dhrs1

DIOPT Version :9

Sequence 1:	NP_001262292.1	Gene:	CG31549 / 40689	FlyBaseID:	FBgn0051549	Length:	257	Species:	Drosophila melanogaster
Sequence 2:	NP_001007622.1	Gene:	Dhrs1 / 290234	RGDID:	1359172	Length:	313	Species:	Rattus norvegicus

Alignment Length:	208	Identity:	71/208 - (34%)
Similarity:	104/208 - (50%)	Gaps:	11/208 - (5%)

- Green bases have known domain annotations that are detailed below.

  Fly     3 SFKDKVIIVTGASSGIGASAAVHLAKLGGLLVIVGRNEEKLKETADNIVAAGGATPLELQADMTK 67
            :.|.:|.:|||||.|||...|:.|.:.|..:.|.||:.:.|:.||....:.||.. :.:..|.::
  Rat     4 TMKGQVCVVTGASRGIGRGIALQLCQAGATVYITGRHLDTLRATAQEAQSLGGRC-VPVVCDSSQ 67

  Fly    68 EAEVQQIV-GATLAKHGRIDVLVNNA-----GILE--TGSIEATSLEQFDRLMNTNVRSLYQLTM 124
            |:||:.:. .....:.||:|||||||     .||.  |.|........:|.:.|..:|..|..::
  Rat    68 ESEVKSLFEQVDREQQGRLDVLVNNAYAGVQAILNTTTKSFWEAPASLWDDINNVGLRGHYLCSV 132

  Fly   125 LATPELVKT-KGNIVNVSSVCGLRAFPGVLAYNVSKAAVDQFTACIALELAPKGVRVNAVNPGVI 188
            .....:|.. ||.||.|||..||:....| .|.|.|||.|:..|..|.||...||...::.||::
  Rat   133 YGARLMVPAGKGLIVVVSSPGGLQHMFNV-PYGVGKAACDKLAADCAHELRRHGVSYVSLWPGLV 196

  Fly   189 VTDIHKRGGMDEE 201
            .|::.|.....||
  Rat   197 QTEMVKEYVAKEE 209

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG31549	NP_001262292.1	NADB_Rossmann	4..254	CDD:304358	71/207 (34%)
CG31549	NP_001262292.1	fabG	4..251	CDD:235975	71/207 (34%)
Dhrs1	NP_001007622.1	PRK08303	1..271	CDD:236229	71/208 (34%)
Dhrs1	NP_001007622.1	DHRS1-like_SDR_c	5..271	CDD:187664	71/207 (34%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG0725
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	2	1.900