DRSC/TRiP Functional Genomics Resources

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Protein Alignment CG31549 and DECR2

DIOPT Version :9

Sequence 1:NP_001262292.1 Gene:CG31549 / 40689 FlyBaseID:FBgn0051549 Length:257 Species:Drosophila melanogaster
Sequence 2:NP_065715.1 Gene:DECR2 / 26063 HGNCID:2754 Length:292 Species:Homo sapiens


Alignment Length:253 Identity:76/253 - (30%)
Similarity:118/253 - (46%) Gaps:16/253 - (6%)


- Green bases have known domain annotations that are detailed below.


  Fly     5 KDKVIIVTGASSGIGASAAVHLAKLGGLLVIVGRNEEKLKETADNIVAAGGATPLELQADMTKEA 69
            :|||..:||..||||...|....:.|...||..|:..::...|..:..|.|...|.|..|:....
Human    27 RDKVAFITGGGSGIGFRIAEIFMRHGCHTVIASRSLPRVLTAARKLAGATGRRCLPLSMDVRAPP 91

  Fly    70 EVQQIVGATLAKHGRIDVLVNNAG---ILETGSIEATSLEQFDRLMNTNVRSLYQLTMLATPELV 131
            .|...|...|.:.||||:|:|.|.   :...|   |.|...|..:|:.:....:.::.:...:..
Human    92 AVMAAVDQALKEFGRIDILINCAAGNFLCPAG---ALSFNAFKTVMDIDTSGTFNVSRVLYEKFF 153

  Fly   132 KTKGN-IVNVSSVCGLRAFPGVLAYNVSKAAVDQFTACIALELAPKGVRVNAVNPGVI--VTDIH 193
            :..|. |||:::..|.|.....:....:|||||..|..:|:|..|:.:|||::.||.|  ...:.
Human   154 RDHGGVIVNITATLGNRGQALQVHAGSAKAAVDAMTRHLAVEWGPQNIRVNSLAPGPISGTEGLR 218

  Fly   194 KRGGMDEETYAKFLEHCKITHA-LGRPGDVKEVAAAIAFLASDQASFTTGISLPVDGG 250
            :.||.....      ..|:|.: |.|.|:..|:|.::.:|||..||:.||..|..|||
Human   219 RLGGPQASL------STKVTASPLQRLGNKTEIAHSVLYLASPLASYVTGAVLVADGG 270

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
CG31549NP_001262292.1 NADB_Rossmann 4..254 CDD:304358 76/253 (30%)
fabG 4..251 CDD:235975 76/253 (30%)
DECR2NP_065715.1 TER_DECR_SDR_a 26..273 CDD:187627 76/253 (30%)
Substrate binding 126..128 1/1 (100%)
Microbody targeting signal. /evidence=ECO:0000250 290..292
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 1 0.900 - - E2759_KOG0725
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 00.000 Not matched by this tool.
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
User_Submission 00.000 Not matched by this tool.
10.900

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