Protein Alignment CG31549 and Hsd17b8

DIOPT Version :10

• Sequence 1: NP_730972.2
• Gene: CG31549 / 40689
• FlyBaseID: FBgn0051549
• Length: 257
• Species: Drosophila melanogaster
• Sequence 2: NP_038571.2
• Gene: Hsd17b8 / 14979
• MGIID: 95911
• Length: 259
• Species: Mus musculus
• Alignment Length: 255
• Identity: 78/255 - (30%)
• Similarity: 124/255 - (48%)
• Gaps: 15/255 - (5%)

  Fly     5 KDKVIIVTGASSGIGASAAVHLAKLGGLLVIVGRNEEKLKETADNIVAAG---GA---TPLELQA 63
            :..:.:||||.||||.:.:|.||..|..:.....:....::|...:.:.|   ||   .....||
Mouse     8 RSALALVTGAGSGIGRAISVRLAAEGAAVAACDLDGAAAQDTVRLLGSPGSEDGAPRGKHAAFQA 72

  Fly    64 DMTKEAEVQQIVGATLAKHGR-IDVLVNNAGILETGSIEATSLEQFDRLMNTNVRSLYQLTMLAT 127
            |:::....::::....|...| ..|:|:.|||.....:...|.|.:||::..|::..:.:|..|.
Mouse    73 DVSQGPAARRLLEEVQACFSRPPSVVVSCAGITRDEFLLHMSEEDWDRVIAVNLKGTFLVTQAAA 137

  Fly   128 PELVKT--KGNIVNVSSVCGLRAFPGVLAYNVSKAAVDQFTACIALELAPKGVRVNAVNPGVIVT 190
            ..||.:  :|:|:|:||:.|.....|...|..|||.|...|...|.||...|:|.|:|.||.|.|
Mouse   138 QALVSSGGRGSIINISSIIGKVGNIGQTNYASSKAGVIGLTQTAARELGRHGIRCNSVLPGFIAT 202

  Fly   191 DIHKRGGMDEETYAKFLEHCKITHALGRPGDVKEVAAAIAFLASDQASFTTGISLPVDGG 250
            .      |.::...|..:.......||..||.::||..:|||||:.:.:.||.|:.|.||
Mouse   203 P------MTQKMPEKVKDKVTAMIPLGHMGDPEDVADVVAFLASEDSGYITGASVEVSGG 256

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG31549	NP_730972.2	Rossmann-fold NAD(P)(+)-binding proteins	4..254	CDD:473865	78/255 (31%)
Hsd17b8	NP_038571.2	Rossmann-fold NAD(P)(+)-binding proteins	11..258	CDD:473865	78/252 (31%)