DRSC/TRiP Functional Genomics Resources

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Protein Alignment CG31549 and DHRS1

DIOPT Version :9

Sequence 1:NP_001262292.1 Gene:CG31549 / 40689 FlyBaseID:FBgn0051549 Length:257 Species:Drosophila melanogaster
Sequence 2:NP_001129522.1 Gene:DHRS1 / 115817 HGNCID:16445 Length:313 Species:Homo sapiens


Alignment Length:210 Identity:68/210 - (32%)
Similarity:101/210 - (48%) Gaps:23/210 - (10%)


- Green bases have known domain annotations that are detailed below.


  Fly     7 KVIIVTGASSGIGASAAVHLAKLGGLLVIVGRNEEKLKETADNIVAAGGATPLELQADMTKEAEV 71
            :|.:|||||.|||...|:.|.|.|..:.|.||:.:.|:..|....:.||.. :.:..|.::|:||
Human     8 QVCVVTGASRGIGRGIALQLCKAGATVYITGRHLDTLRVVAQEAQSLGGQC-VPVVCDSSQESEV 71

  Fly    72 QQIV-GATLAKHGRIDVLVNNA-----GILET--GSIEATSLEQFDRLMNTNVRSLYQLTMLATP 128
            :.:. .....:.||:|||||||     .||.|  .:...|....:|.:.|..:|..|..::....
Human    72 RSLFEQVDREQQGRLDVLVNNAYAGVQTILNTRNKAFWETPASMWDDINNVGLRGHYFCSVYGAR 136

  Fly   129 ELVKT-KGNIVNVSSVCGLRAFPGVL------AYNVSKAAVDQFTACIALELAPKGVRVNAVNPG 186
            .:|.. :|.||.:||       ||.|      .|.|.|||.|:..|..|.||...||...::.||
Human   137 LMVPAGQGLIVVISS-------PGSLQYMFNVPYGVGKAACDKLAADCAHELRRHGVSCVSLWPG 194

  Fly   187 VIVTDIHKRGGMDEE 201
            ::.|::.|.....||
Human   195 IVQTELLKEHMAKEE 209

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
CG31549NP_001262292.1 NADB_Rossmann 4..254 CDD:304358 68/210 (32%)
fabG 4..251 CDD:235975 68/210 (32%)
DHRS1NP_001129522.1 PRK08303 1..271 CDD:236229 68/210 (32%)
DHRS1-like_SDR_c 5..271 CDD:187664 68/210 (32%)


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 1 0.900 - - E2759_KOG0725
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 00.000 Not matched by this tool.
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
User_Submission 00.000 Not matched by this tool.
10.900

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