DRSC/TRiP Functional Genomics Resources

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back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits


Protein Alignment Atu and VIP4

DIOPT Version :9

Sequence 1:NP_524240.1 Gene:Atu / 40684 FlyBaseID:FBgn0019637 Length:725 Species:Drosophila melanogaster
Sequence 2:NP_851237.1 Gene:VIP4 / 836236 AraportID:AT5G61150 Length:625 Species:Arabidopsis thaliana


Alignment Length:638 Identity:146/638 - (22%)
Similarity:247/638 - (38%) Gaps:131/638 - (20%)


- Green bases have known domain annotations that are detailed below.


  Fly   127 RRSGSPQSRKSGSTHSRRSGSAHSRRSGSARSRKSGSAQSDRSESRSRSHSGSLKGNEESRSNSP 191
            |:.........|.......|.|.....|.|      .|:||..:.......|..:|..|..|...
plant    33 RQPNYASDEAEGGVEPEGEGEAEVEVHGEA------EAESDGEQGDVELDPGESEGEREQSSQEA 91

  Fly   192 NLQIDVERANSKSGSRSRSRSRSGSRTSRSRSKTGTPSPNRSRSGSASGSGSDVGVPKKKARKAS 256
            :.|.:.|..:|.|.::....   |.|.::.|.:....| ...|||                    
plant    92 DPQEESEARDSDSDNKEEEH---GGRVAKKRRQEVVES-GSERSG-------------------- 132

  Fly   257 GSDQEKKKSGSDSDIEE-----SPTKAKKSRLIDTDSDSNQDVGKKAPAAADIFGDADDISDDE- 315
                ||.....|.::::     ||::.|:...: ..||.|         ..::||.:||...:| 
plant   133 ----EKHYESEDEEVDQTRSPRSPSEEKEEVQV-AQSDVN---------IRNVFGSSDDEDAEEY 183

  Fly   316 --DEAGPAARKSPVRSKSRSQ---------------SKSHSHSRSMSHSRSRSRSRS-RDKVESQ 362
              ::......:||:..:..|:               .:...:.....|..:|.|.|. ...:|.:
plant   184 VRNDVEQDEHRSPIEDEEGSEKDLRPDDMVLDDIIPEEDPQYESEAEHVEARYRERPVGPPLEVE 248

  Fly   363 VESAPKEDEPEPLPETRIDVEIPRISADLGKEQHFIKLPNFLSVVTHPFDPETYEDEIDEEETM- 426
            |...|...:|                    .:.:.||:.|.:.:...|||.:|:   ::|:..| 
plant   249 VPFRPPPGDP--------------------VKMNMIKVSNIMGIDPKPFDAKTF---VEEDTFMT 290

  Fly   427 DEEG-RQRIKLKVSNTIRWREYMNNKGDMVRESNARFVRWSDGSMSLHLGNEIFDAYRQPLLGDH 490
            ||.| :.||:|. :|.:|.|...:..|....|||||||||||||:.|.:|||:.:...|....|.
plant   291 DEPGAKNRIRLD-NNIVRHRFVKSRDGKTYSESNARFVRWSDGSLQLLIGNEVLNITEQDAKEDQ 354

  Fly   491 NHLFVRQGTG-LQGQSVFRTKLTFRPHSTESFTHKKMTMSLADRSSKTSGIK-ILTQVGKDPTTD 553
            ||||::...| ||.|.....|:.|.|.|..|.:|:.:|..:..|..|...:| .:|.:  ||..:
plant   355 NHLFIKHEKGILQSQGRILKKMRFTPSSLTSNSHRLLTAIVESRQKKAFKVKNCVTDI--DPERE 417

  Fly   554 RPTQLREEEAKLRQAMR-NQHKSLPKKKKP----------GAGEPLIGGGTSSYQHDEGSDDE-- 605
            :..:.:.|...|:.:.: :|.:...|:|.|          |..|..:......|:.:.|.:::  
plant   418 KEKREKAESQNLKASTKLSQAREKIKRKYPLPVERRQLSTGYLEDALDEDDEDYRSNRGYEEDLE 482

  Fly   606 -NAISLSAIKNRYKKGSG-AGQAEV------KASTIYSSDEDEGSDFEARRSKKVDKAKASKALR 662
             .|.....|.|..|...| .|::.:      :....||..|.|.|::|....:: :|:.|....:
plant   483 AEAQRERRILNAKKSHKGIPGRSSMTSARPSRRQMEYSESEREESEYETEEEEE-EKSPARGRGK 546

  Fly   663 DSDSE----SDAGSAKSGHSNKSGGEGGSASGSENEGSQKSGGGSSKSASGSG 711
            ||:.|    ::....:.|.||:...|       :.|..:.:||.:.|...|||
plant   547 DSEDEYEEDAEEDEEERGKSNRYSDE-------DEEEEEVAGGRAEKDHRGSG 592

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
AtuNP_524240.1 Leo1 396..550 CDD:281933 57/157 (36%)
VIP4NP_851237.1 2A1904 <61..250 CDD:273344 41/232 (18%)
Leo1 262..422 CDD:367768 59/165 (36%)


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Domainoid 1 1.000 92 1.000 Domainoid score I2593
eggNOG 1 0.900 - - E1_KOG2428
Hieranoid 1 1.000 - -
Homologene 00.000 Not matched by this tool.
Inparanoid 1 1.050 127 1.000 Inparanoid score I1921
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 1 1.000 - - FOG0004097
OrthoInspector 1 1.000 - - otm3196
orthoMCL 00.000 Not matched by this tool.
Panther 1 1.100 - - LDO PTHR23146
Phylome 00.000 Not matched by this tool.
SonicParanoid 1 1.000 - - X4466
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
88.050

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