DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment Atu and CG10887

DIOPT Version :9

Sequence 1:	NP_524240.1	Gene:	Atu / 40684	FlyBaseID:	FBgn0019637	Length:	725	Species:	Drosophila melanogaster
Sequence 2:	NP_650866.1	Gene:	CG10887 / 42399	FlyBaseID:	FBgn0038773	Length:	676	Species:	Drosophila melanogaster

Alignment Length:	754	Identity:	181/754 - (24%)
Similarity:	291/754 - (38%)	Gaps:	196/754 - (25%)

- Green bases have known domain annotations that are detailed below.

  Fly    64 SARSGSAESRH------SQLSGSARSKRSRSAHSRRSGSARSRKSGTPESPQSHRSGSLQSRKSG 122
            |:.|..|.:|.      |.:.......::|..|..||.|..|..:..|||     .|.|:||
  Fly    17 SSESWPAFNRRSPNPSFSSVDQQGNKTKARRQHQSRSHSFHSTANSVPES-----QGPLESR--- 73

  Fly   123 SPQSRRSGSPQSRKSGSTHSRRSGSAHSRRSGSARSRKSGSAQSDRSESRSRSHSGSLKGNEESR 187
                       |..:..|.|:......|..:.|..|..|..:..|..||.|.|.|.||..:
  Fly    74 -----------SDLNAKTSSKSERPYISTSNSSWTSESSSGSPPDSGESSSFSTSSSLSSS---- 123

  Fly   188 SNSPNLQIDVERANSKSGSRSRSRSRSGSRTSRSRSKTGTPSPNRSRSGSASGSGSDVGVPKKKA 252
                  .:......|.:.|..:|.|...:.|:.|..:.|         |..|.|.||
  Fly   124 ------LLCAPEPKSINWSNPKSSSNISNETTTSAGQVG---------GIPSFSESD-------- 165

  Fly   253 RKASGSDQEKKKSGSDSDIEESPTKAKKSRLIDT--DSDSNQDVGKKA-------------PAAA 302
                  ||....|.:.|:|.:|.:..:.....:|  |.|:||.:..:.             |::.
  Fly   166 ------DQGSVDSETVSNIRKSTSLIELKDNFNTIIDEDNNQQLSNEGNILSPGTVSISNFPSSN 224

  Fly   303 DIF-GDADDISDD------------------EDEAGP----------------AARKSPVRSKSR 332
            ::. |..|::..|                  |.|..|                ..|.:||.....
  Fly   225 EVANGLIDEMEQDLLSKQHSTSTPINKSNTMEKELLPLQCSSFPPTSSEGNILKPRVNPVPLGPS 289

  Fly   333 SQSKSHSHSRSMSHSRSRSRSR-SRDKVESQVESAPKED----------------------EPEP 374
            |.::..|:.::.:..:..|:.| |.|:.||.|.|....|                      |...
  Fly   290 SNTEYESNGKNYNIEKRLSQLRYSSDEKESDVLSYASSDSLDLNFDYGDNAKNQNGNGMNGEVNG 354

  Fly   375 LPETRI-DVEIPR--ISADL-----------------GKEQHFIKLPNFLSVVTHPFDPETYEDE 419
            ..|::: |:|..|  ...|:                 |..| |:|:|.|:.|.:..:.|||::|.
  Fly   355 DKESQVLDIEEQRKPFEKDVAVKFQTTITTQNCGLLKGPSQ-FLKMPYFIPVESKAYVPETFQDR 418

  Fly   420 IDEEETMDEEGRQRIKLKVSNTIRWREYMNNKGDMVRESNARFVRWSDGSMSLHLGNEIFDAYRQ 484
            :.:.:..||:.|:....::..|:||||..|.    .:||||:.|||||||.:.|:|||:||....
  Fly   419 MTKNDLKDEQSREDFINRLKATVRWRENENK----TKESNAKIVRWSDGSETFHVGNEVFDMMHH 479

  Fly   485 PLLGDHNHLFVRQGTGLQGQSVFRTKLTFRPHSTESF--THKKMTMSLADRSSKTSGIKILTQVG 547
            |:..:.|||:||.|:..|.|.:.:.|||.||....:|  :|.:...:.|....::..:|::|.:|
  Fly   480 PVTVNQNHLYVRLGSFYQPQGLIQNKLTVRPMLDSNFGQSHVQALRNRATNKPQSGCVKVITNMG 544

  Fly   548 KDPTTDRPTQLREEEAKLRQAMRNQHKSLPKKKKPGAGEPLIGGGTSSYQHDEGSDDENAISLSA 612
            .:|..|...:::||.:||||..|.::::|.|...|           ...:|.:|||...|
  Fly   545 SNPEHDHDRRMKEELSKLRQEGREKNRALMKNHPP-----------KRDRHYQGSDHNVA----- 593

  Fly   613 IKNRYKKGSGAGQAEVKASTIYSSDEDEGSDFEARRSKKVDKAKASKALRDSDSESDAGSAKSGH 677
                  |.:||          :..|:.||:|.|...:.:|    .::.:|..:...|.....:..
  Fly   594 ------KNAGA----------FEEDDGEGADCETSSALEV----TNEPMRSEEDTEDHMDDDASW 638

  Fly   678 SNKSGGEGGSASGSENEGSQKSGGGSSKSASGSGSGSGS 716
            |:.:..|.|..|.||::  ...||...|......|||.|
  Fly   639 SSPNSQEEGKQSSSEDD--LPIGGAIRKPTRLVYSGSDS 675

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Atu	NP_524240.1	Leo1	396..550	CDD:281933	55/155 (35%)
CG10887	NP_650866.1	Leo1	396..548	CDD:281933	55/155 (35%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45447476
Domainoid	1	1.000	92	1.000	Domainoid score	I2593
eggNOG	1	0.900	-	-		E1_KOG2428
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0004097
OrthoInspector	1	1.000	-	-		otm3196
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR23146
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	7	6.840