Protein Alignment Atu and leo-1

DIOPT Version :9

• Sequence 1: NP_524240.1
• Gene: Atu / 40684
• FlyBaseID: FBgn0019637
• Length: 725
• Species: Drosophila melanogaster
• Sequence 2: NP_502135.1
• Gene: leo-1 / 178052
• WormBaseID: WBGene00007110
• Length: 430
• Species: Caenorhabditis elegans
• Alignment Length: 480
• Identity: 170/480 - (35%)
• Similarity: 250/480 - (52%)
• Gaps: 75/480 - (15%)

  Fly   214 SGSRTSRSRSKTGTPSPNRSRSGSASGSGSDVGVPKKKARKASGSDQEKKK---SGSDSDIEESP 275
            |.|..:...|..|||    .:|.:.|..||....|||:       :..||:   :.||.|.:..|
 Worm     2 SSSEGNSDASAPGTP----VKSSTPSSRGSSPDSPKKQ-------EPSKKRAILNESDDDDDSRP 55

  Fly   276 TKAKKSRLIDTDSDSNQDVG---KKAP-AAADIFGDADDISDDE-DEAGPAARKSPVRSKSRSQS 335
            .   ..:|.|:..|:....|   |.:| |...:|||....|||: |..|     .|..|.:|::
 Worm    56 A---PRQLSDSSDDNIHPRGGGEKSSPGAGGGLFGDLSGSSDDDSDREG-----KPKESNTRAR- 111

  Fly   336 KSHSHSRSMSHSRSRSRSRSRDKVESQVESAPKE-DEPEPLPETRIDVEI--PRISADLGKE-QH 396
                    :|.|.:.||....| ::..|.:.|.| ||.|...|...|.|:  .|::.:...: .|
 Worm   112 --------LSDSDAESRGSLND-LQGIVMANPDEIDEDEKAKEHVHDTEMVTGRVTLEYAADPPH 167

  Fly   397 FIKLPNFLSVVTHPFDPETY-EDEIDEEETMDEEGRQRIKLKVSNTIRWREYMNNKGDMVRESNA 460
            |:::||||||.||||||:.| |||.||:..:|:|||.|:||:|.||:|||...:..|..:|||||
 Worm   168 FVRMPNFLSVATHPFDPQHYEEDEDDEQAKLDDEGRTRLKLRVENTLRWRVRKDENGKEIRESNA 232

  Fly   461 RFVRWSDGSMSLHLGNEIFDAYRQPLLGDH-NHLFVRQGTGLQGQSVFRTKLTFRPHSTESFTHK 524
            :.|:|.||:|||:||||||:....||..:: .||:|:|.|.:..|:|...::|||||||:|.||:
 Worm   233 KIVKWDDGTMSLYLGNEIFEVSLVPLNSNNLPHLYVKQPTLMSAQAVLTHRMTFRPHSTDSQTHR 297

  Fly   525 KMTMSLADRSSKTSGIKILTQVGKDPTTDRPTQLREEEAKLR------QAMRNQHKSLPKKKKPG 583
            |:|:::||||.|.:.:|::..||::|...|....|:||..||      |.:||..|
 Worm   298 KVTLNMADRSRKNAQVKVMDDVGQNPEITRRENARKEEESLRAHIRRTQMVRNNFK--------- 353

  Fly   584 AGEPLIGGGTSSYQHDEGSDDENAISLSAIKNRYKK----GSGAGQAEVKASTIYSSDEDEGSDF 644
                 :.|...:.|:   ||||: :..|:.|.:.|:    |:.:...:..|.|...|..|..||.
 Worm   354 -----VRGPRYAGQY---SDDED-MPTSSRKGKKKEAPIIGASSESEDDHADTTKKSGSDSDSDE 409

  Fly   645 EARRSKKVDKAKASKALRDSDSESD 669
            |.|:.|:..|    |.:..||.|||
 Worm   410 EYRKRKQQQK----KQIVTSDEESD 430

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Atu	NP_524240.1	Leo1	396..550	CDD:281933	81/155 (52%)
leo-1	NP_502135.1	Leo1	167..328	CDD:281933	82/160 (51%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C160158876
Domainoid	1	1.000	180	1.000	Domainoid score	I2092
eggNOG	1	0.900	-	-		E1_KOG2428
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	226	1.000	Inparanoid score	I2233
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0004097
OrthoInspector	1	1.000	-	-		oto19119
orthoMCL	1	0.900	-	-		OOG6_104699
Panther	1	1.100	-	-	LDO	PTHR23146
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R1979
SonicParanoid	1	1.000	-	-		X4466
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	12	11.820