Protein Alignment Rga and Cnot2

DIOPT Version :10

• Sequence 1: NP_730966.1
• Gene: Rga / 40683
• FlyBaseID: FBgn0017550
• Length: 585
• Species: Drosophila melanogaster
• Sequence 2: NP_001032936.2
• Gene: Cnot2 / 72068
• MGIID: 1919318
• Length: 550
• Species: Mus musculus
• Alignment Length: 594
• Identity: 194/594 - (32%)
• Similarity: 276/594 - (46%)
• Gaps: 163/594 - (27%)

  Fly     1 MANLNFQQPPRSIANAALAGRTTGGFGGSSLAGHVTPTSGMFQTDFANSYPGTANYGQAPQQQQQ 65
            |:| |..|..||::.            |:.|..|||||:|:  ...:...|.:.:.|..|...:.
Mouse    99 MSN-NTPQLNRSLSQ------------GTQLPSHVTPTTGV--PTMSLHTPPSPSRGILPMNPRN 148

  Fly    66 QQQQPQLS-----PNRNAQLSVGGPAISSGNRNAN--LFGQRQFVERRAMQGLGSGPMSNMGNFM 123
            .....|:.     |:|...:|..|  :.|.||::.  :...:|...|:.              |.
Mouse   149 MMNHSQVGQGIGIPSRTNSMSSSG--LGSPNRSSPSIICMPKQQPSRQP--------------FT 197

  Fly   124 QTGRGGYGTGGGGGGPLNN---FHVFGGGGGSDTSTPALLDPTEFPSLT--NARGQNDQTLPQSN 183
            .....|:|........:||   .::|.|..||:..|.  ||.::||:|.  |.|..:....|..|
Mouse   198 VNSMSGFGMNRNQAFGMNNSLSSNIFNGTDGSENVTG--LDLSDFPALADRNRREGSGNPTPLIN 260

  Fly   184 PLQPPGSKPYGNFFTSFGMVKQPTSEQS-EFTMSNEDFPALPGTQNSDGTTNAVGSVAGTGGSGG 247
            ||  .|..||      .|||.:|.:||| :|::.|||||||||:...|.|::...|.:....||
Mouse   261 PL--AGRAPY------VGMVTKPANEQSQDFSIHNEDFPALPGSSYKDPTSSNDDSKSNLSTSG- 316

  Fly   248 ASTENHLDGTEKPMNSIVVSGSASGSSGSNVGVVGGNGLGAVGSGIGGLAVGGGGGAGSSGGGGV 312
             .|.:..||.:.|
Mouse   317 -KTTSSTDGPKFP---------------------------------------------------- 328

  Fly   313 GGNAASGVVGGSHVGLVGSNSGIGGVNSVPNSNAMMGVGGGLGSGSGSSGSGAGGEHLNDNSSND 377
                                                        |..||           .:.|:
Mouse   329 --------------------------------------------GDKSS-----------TTQNN 338

  Fly   378 KLVKSGVQTSPDGKVTNIPATMVNNQFGMVGLLTFIRAAETDPNLVTLSLGTDLTGLGLNLNSQE 442
            ...|.|:|..|||:|||||..||.:||||:|||||||||||||.:|.|:||:|||.|||||||.|
Mouse   339 NQQKKGIQVLPDGRVTNIPQGMVTDQFGMIGLLTFIRAAETDPGMVHLALGSDLTTLGLNLNSPE 403

  Fly   443 SLHTTFAGPFVAQPCRAQDVEFNVPPEYLINFAIRDKLTAPVLKKLQEDLLFFLFYTNIGDMMQL 507
            :|:..||.|:.:.|||.||::|:||.|||.|..|||||.|..|.:..|||||:|:|.|.||::||
Mouse   404 NLYPKFASPWASSPCRPQDIDFHVPSEYLTNIHIRDKLAAIKLGRYGEDLLFYLYYMNGGDVLQL 468

  Fly   508 MAAAELHSREWRYHVEEKIWITRIPGIDQYEKNGTKERGTFYYFDAQSWKRLSKVFQIDPEKLDK 572
            :||.||.:|:||||.||::||||.||::...|..|.||||:|:||..:|::::|.|.::.:||::
Mouse   469 LAAVELFNRDWRYHKEERVWITRAPGMEPTMKTNTYERGTYYFFDCLNWRKVAKEFHLEYDKLEE 533

  Fly   573 CPNISAFMN 581
            .|::.:..|
Mouse   534 RPHLPSTFN 542

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Rga	NP_730966.1	NOT2_3_5	445..568	CDD:461199	63/122 (52%)
Cnot2	NP_001032936.2	NOT2_3_5	406..529	CDD:461199	63/122 (52%)