Protein Alignment Rga and ntl-2

DIOPT Version :10

• Sequence 1: NP_730966.1
• Gene: Rga / 40683
• FlyBaseID: FBgn0017550
• Length: 585
• Species: Drosophila melanogaster
• Sequence 2: NP_494772.1
• Gene: ntl-2 / 173773
• WormBaseID: WBGene00003825
• Length: 444
• Species: Caenorhabditis elegans
• Alignment Length: 547
• Identity: 147/547 - (26%)
• Similarity: 220/547 - (40%)
• Gaps: 196/547 - (35%)

  Fly    48 NSYPGTANYGQAPQQQQQQQQQPQLSPNRNAQLSVGGPAISSGNRNANLFGQRQFVERRAMQGLG 112
            ||..|.|...:.||.||....                   |:.:.||.:..:.||      ..||
 Worm     2 NSVGGVATERRLPQTQQFLSH-------------------SNFHSNATIIDESQF------PSLG 41

  Fly   113 SGPMSNMGNFMQTGRGGYGTGGGGGGPLNNFHVFGGGGGSDTSTPALLDPTEFPSLTNARGQNDQ 177
            :             :|....||||..|:                     ||....:.|
 Worm    42 A-------------KGTSSLGGGGFSPI---------------------PTTSGGVLN------- 65

  Fly   178 TLPQSNP------LQPPGSKPYGNFFTSFGMVKQPTSEQSEFTMSNEDFPALPGTQNSDGTTNAV 236
             :.||:|      .|.|.   |.|...|     .|:....||.:.|||||||||.
 Worm    66 -VAQSSPSRDLYGAQRPN---YANLMRS-----DPSLTNPEFQIQNEDFPALPGV---------- 111

  Fly   237 GSVAGTGGSGGASTENHLDGTEKPMNSIVVSGSASGSSGSNVGVVGGNGLGAVGSGIGGLAVGGG 301
                   |||         .|::.|.
 Worm   112 -------GSG---------QTQRSML--------------------------------------- 121

  Fly   302 GGAGSSGGGGVGGNAASGVVGGSHVGLVGSNSGIGGVNSVPNSNAMMGVGGGLGSGSGSSGSGAG 366
                        |:..:.::...|                     .:...|.||....|..||
 Worm   122 ------------GDQLANMLADDH---------------------QVDFAGPLGDCDPSRLSG-- 151

  Fly   367 GEHLNDNSSNDKLVKSGVQTSPDGKVTNIPATMVNNQFGMVGLLTFIRAAETDPNLVTLSLGTDL 431
               ::.||....:  .|:.|.|||:||||||:|:::||||.||:|::|..: :|::|:|:||.||
 Worm   152 ---ISRNSQEGPM--HGIITHPDGEVTNIPASMLDDQFGMAGLVTYLRTVD-NPSIVSLALGYDL 210

  Fly   432 TGLGLNLN-SQESLHTTFAGPFVAQPCRAQDVEFNVPPEYLINFAIRDKLTAPVLKKLQEDLLFF 495
            |.|||||| |:..|:..|.||:...|.||.:::..||.||:.:..|||||....|.|:.||:||:
 Worm   211 TTLGLNLNLSERKLYMNFGGPWADSPIRAHELDVKVPEEYMTHNHIRDKLPPLRLNKVSEDVLFY 275

  Fly   496 LFYTNIGDMMQLMAAAELHSREWRYHVEEKIWITRIPGIDQY----EKNGTKERGTFYYFDAQSW 556
            |||....::.|:.||.||::||||:|..|::|:||    .||    |:.|..|:|.:..||...|
 Worm   276 LFYNCPNEIYQVAAACELYAREWRFHKSEQVWLTR----SQYGGVKEQTGNYEKGHYNVFDQMQW 336

  Fly   557 KRLSKVFQIDPEKLDKCPNISAFMNGQ 583
            :::.|..:::.::|:..|.:...::||
 Worm   337 RKIPKELKLEYKELEDRPKMPQSVSGQ 363

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Rga	NP_730966.1	NOT2_3_5	445..568	CDD:461199	48/126 (38%)
ntl-2	NP_494772.1	NOT2_3_5	228..348	CDD:461199	48/123 (39%)