Protein Alignment SecS and SGPL1

DIOPT Version :9

• Sequence 1: NP_649556.3
• Gene: SecS / 40681
• FlyBaseID: FBgn0037347
• Length: 478
• Species: Drosophila melanogaster
• Sequence 2: NP_003892.2
• Gene: SGPL1 / 8879
• HGNCID: 10817
• Length: 568
• Species: Homo sapiens
• Alignment Length: 443
• Identity: 94/443 - (21%)
• Similarity: 154/443 - (34%)
• Gaps: 120/443 - (27%)

  Fly    27 SKQRSF----KELLEKRKLPKNGWSDERIEELVHMLASLDSNNYPHKVGLGEREARIACKLVARR 87
            ||..||    ||.:  :.||..|.|...:.|.:...:|:|:         ..:|.|.:
Human   100 SKNMSFLKVDKEYV--KALPSQGLSSSAVLEKLKEYSSMDA---------FWQEGRAS------- 146

  Fly    88 HYNFGHGIGRSGD--LLEAQPKAAGSTLLARLTNALILDLIRGI----------------GLPSC 134
                  |...||:  |.|...||.|.   ...:|.|..|:..|:                |.|..
Human   147 ------GTVYSGEEKLTELLVKAYGD---FAWSNPLHPDIFPGLRKIEAEIVRIACSLFNGGPDS 202

  Fly   135 AGCFLVPMCTGMTLTLCLQSLRKR--------------RPGARYVLWSRIDQKSCFKAITATGLV 185
            .||    :.:|.|.::.:.....|              .|.:.:..::        ||.:..|:.
Human   203 CGC----VTSGGTESILMACKAYRDLAFEKGIKTPEIVAPQSAHAAFN--------KAASYFGMK 255

  Fly   186 PVVIPCLIKGESLNTNVDLFREKIKSLGVDSILCLYTTTSCFAPRNSDDIAEVSKLSKQWQIPHL 250
            .|.:|..   :.:..:|...|..| |.....::|   :|..|.....|.:.||:||:.:::||..
Human   256 IVRVPLT---KMMEVDVRAMRRAI-SRNTAMLVC---STPQFPHGVIDPVPEVAKLAVKYKIPLH 313

  Fly   251 VNNAYGLQAKEIVNQLECAN---------RVGRIDYFVQSSDKNLLVPVGSAIV-------ASFN 299
            |:...|   ..::..:|.|.         ||..:......:.|....|.||::|       .::.
Human   314 VDACLG---GFLIVFMEKAGYPLEHPFDFRVKGVTSISADTHKYGYAPKGSSLVLYSDKKYRNYQ 375

  Fly   300 ESVLHD------VASTYAGRASGSQSLDVLMTLLSLGRNGFRLLFDQRGENFNYLRENLRK---- 354
            ..|..|      .:.|.||...|..|......|:..|.||:.....|..:...:|:..|..
Human   376 FFVDTDWQGGIYASPTIAGSRPGGISAACWAALMHFGENGYVEATKQIIKTARFLKSELENIKGI 440

  Fly   355 --FAEPR-GEIVIDSRFNSISLAITLATLAG---DQMK---SITKLGSMLHMR 398
              |..|: ..|.:.||...|.....|.|..|   :|::   ||....::||.|
Human   441 FVFGNPQLSVIALGSRDFDIYRLSNLMTAKGWNLNQLQFPPSIHFCITLLHAR 493

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
SecS	NP_649556.3	AAT_I	12..457	CDD:302748	94/443 (21%)
SGPL1	NP_003892.2	DOPA_deC_like	144..507	CDD:99743	80/388 (21%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0076
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	1	0.900