Protein Alignment SecS and GAD1

DIOPT Version :9

• Sequence 1: NP_649556.3
• Gene: SecS / 40681
• FlyBaseID: FBgn0037347
• Length: 478
• Species: Drosophila melanogaster
• Sequence 2: NP_013976.1
• Gene: GAD1 / 855291
• SGDID: S000004862
• Length: 585
• Species: Saccharomyces cerevisiae
• Alignment Length: 458
• Identity: 88/458 - (19%)
• Similarity: 135/458 - (29%)
• Gaps: 173/458 - (37%)

  Fly     2 NFEQVNIPEKLVPD-------------NYLQLG-LAAQRSKQRSFKELLEKRKLPKNGWSDERIE 52
            |||  ||..|:|.|             :.:|.| ..:...:..|.:.:..|..:||.|...:...
Yeast    11 NFE--NIAGKVVHDLAGLQLLSNDVQKSAVQSGHQGSNNMRDTSSQGMANKYSVPKKGLPADLSY 73

  Fly    53 ELVHMLASLDSN---------------------------------NYPHKVGLGER--------- 75
            :|:|...:||.|                                 .||..:.|.:|
Yeast    74 QLIHNELTLDGNPHLNLASFVNTFTTDQARKLIDENLTKNLADNDEYPQLIELTQRCISMLAQLW 138

  Fly    76 -----EARIAC-----------------KLVARRHYNFGHGIGRSGDLLEAQPKAAGSTLLARLT 118
                 |..|.|                 |....|..|.|....:...::.:..:.|    |.:.|
Yeast   139 HANPDEEPIGCATTGSSEAIMLGGLAMKKRWEHRMKNAGKDASKPNIIMSSACQVA----LEKFT 199

  Fly   119 NALILDLIRGIGLPSCAGCFLVPMCTGMTLTLCLQSLRKRRPGARYVLWSRIDQKS--CFKAITA 181
            ....::            |.|||:           |.|.........||..:|:.:  ||
Yeast   200 RYFEVE------------CRLVPV-----------SHRSHHMLDPESLWDYVDENTIGCF----- 236

  Fly   182 TGLVPVVIPCLIKGESLNTNVDLFREKIKSLGVDSILCLYTTTSCFAPRNSDDIAEVSKLSKQWQ 246
                 |::.....|...|.      ||:..: :..|...:...|     |:|........|..:.
Yeast   237 -----VILGTTYTGHLENV------EKVADV-LSQIEAKHPDWS-----NTDIPIHADGASGGFI 284

  Fly   247 IP------HLVNNAYGLQAKEIVNQLECANRVG----RIDYFVQSSDKNLLVPVGSAIVASFNES 301
            ||      |:  .|||::            |.|    |:.....|..|..|...|...|...:||
Yeast   285 IPFGFEKEHM--KAYGME------------RWGFNHPRVVSMNTSGHKFGLTTPGLGWVLWRDES 335

  Fly   302 VLHD-----------VASTYAGRAS--GSQSLDVLMTLLSLGRNGFRL-----LFDQRGENFNYL 348
            :|.|           |..|:....|  |.|.:......:|||.:|:|.     ||..|..:|..|
Yeast   336 LLADELRFKLKYLGGVEETFGLNFSRPGFQVVHQYFNFVSLGHSGYRTQFQNSLFVARAFSFELL 400

  Fly   349 REN 351
            ..:
Yeast   401 NSS 403

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
SecS	NP_649556.3	AAT_I	12..457	CDD:302748	82/448 (18%)
GAD1	NP_013976.1	Glu-decarb-GAD	41..522	CDD:130848	79/426 (19%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0076
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.900