Protein Alignment SecS and Tdc1

DIOPT Version :10

• Sequence 1: NP_649556.3
• Gene: SecS / 40681
• FlyBaseID: FBgn0037347
• Length: 478
• Species: Drosophila melanogaster
• Sequence 2: NP_610226.2
• Gene: Tdc1 / 35573
• FlyBaseID: FBgn0259977
• Length: 587
• Species: Drosophila melanogaster
• Alignment Length: 481
• Identity: 103/481 - (21%)
• Similarity: 168/481 - (34%)
• Gaps: 155/481 - (32%)

  Fly     2 NFEQVNIPEKLVPDNYLQLGLAAQRSKQ-RSFKELLEKRKLPKNGWSDERIEELVH-----MLAS 60
            |.|:.::...|.| .||:..|.|...:. ..||::||       .:..:.:..:||     ..|.
  Fly    23 NIEERDVAPTLDP-GYLKKLLPADAPQSPEPFKDVLE-------DFEQKIMPGVVHWNHPKFFAY 79

  Fly    61 LDS-NNYPHKVGLGEREARIACKLVARRHYNFGHGIGRSGDLLEAQPKAAGSTLLARLTNALILD 124
            ..| |::|..:|                 ......||..|....:.|.|      |.|...::..
  Fly    80 FPSGNSFPSVLG-----------------DMLSSAIGSIGFSWASCPAA------AELETIVMNW 121

  Fly   125 LIRGIGLP------------------SCAGCFLVPMCT----------GMTL---TLCLQSLRKR 158
            ..:.:|||                  |.:.|.||.:.|          |.|.   ::.|.||
  Fly   122 YAKALGLPKAFVSDAPGSTGGGALQGSASECVLVSLITARARAISELKGQTSVHDSVFLPSL--- 183

  Fly   159 RPGARYVLWSRIDQKSCFKAITATGLVPVVIPCLIKGESLNTNVDLFREKIK---SLGVDS---I 217
                  :.::..:..|..:..|...||.:.|  :...|.....|||.|:.|:   :.|:..   :
  Fly   184 ------IAYASREAHSSVEKATKMALVKLRI--IDADEHGRMRVDLLRQAIQNDVNAGLTPFFVV 240

  Fly   218 LCLYTTTSCFAPRNSDDIAEVSKLSKQ----WQIPHL----VNNAYGLQAKEIVNQ-LECANRVG 273
            ..:.||..|    ..|||.|:.|:.:|    |.  |:    ..|::.|....:.:. ||.|
  Fly   241 ATVGTTGGC----AFDDITEIGKVCRQVSSIWL--HVDGAYAGNSFILPEMRVFSAGLEYA---- 295

  Fly   274 RIDYFVQSSDKNLLVPVGSAIVASFNESVL--HDVASTYAG--------RASGSQSLDVLMTLLS 328
              |.|..:.:|.||        .:|:.|.|  .||.:..:.        |......:|.....:.
  Fly   296 --DSFNTNPNKLLL--------TNFDASALWVRDVMNLKSALNVNPLYLRHEHLTGVDYRHYGIP 350

  Fly   329 LGRNGFRLL--------FDQRGENFNYLRENL---RKFAEPRGEIVI--DSRF---NSISLAITL 377
            |.|. ||.|        :..||.. .|:|.::   :||     |:::  |.||   |.:.|.:..
  Fly   351 LSRR-FRALKLWFVFRTYGIRGLQ-EYIRNHMALAKKF-----EMLVRKDERFEVRNDVHLGLVC 408

  Fly   378 ATL-AGDQ-----MKSITKLGSMLHM 397
            ..: .||:     :..|...|.| ||
  Fly   409 FRMRTGDEPNHMLLAQINHSGKM-HM 433

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
SecS	NP_649556.3	AAT_I	12..457	CDD:450240	101/471 (21%)
Tdc1	NP_610226.2	Pyridoxal_deC	35..412	CDD:395219	93/445 (21%)