Protein Alignment SecS and GADL1

DIOPT Version :9

• Sequence 1: NP_649556.3
• Gene: SecS / 40681
• FlyBaseID: FBgn0037347
• Length: 478
• Species: Drosophila melanogaster
• Sequence 2: NP_997242.2
• Gene: GADL1 / 339896
• HGNCID: 27949
• Length: 521
• Species: Homo sapiens
• Alignment Length: 282
• Identity: 52/282 - (18%)
• Similarity: 94/282 - (33%)
• Gaps: 96/282 - (34%)

  Fly   222 TTTSCFAPRNSDDIAEVSKLSKQWQIPHLVNNAYGLQAKEIVNQLECANRVGRIDYFVQSSDKNL 286
            |....|.|  .|:||::.:....|.  | |:.::|..|.......:..:.:.|.|....:..|.|
Human   276 TVLGAFDP--LDEIADICERHSLWL--H-VDASWGGSALMSRKHRKLLHGIHRADSVAWNPHKML 335

  Fly   287 LVPVGSAIVASFNESVLHDVASTYAGRAS---------------GSQSLD---------VLMTLL 327
            :..:....:...::|.|  :...|:.:||               |.:|:.         ..||..
Human   336 MAGIQCCALLVKDKSDL--LKKCYSAKASYLFQQDKFYDVSYDTGDKSIQCSRRPDAFKFWMTWK 398

  Fly   328 SLG------------------------RNGFRLLFDQRGEN--FNYLRENLRKFAE-PRGEIVID 365
            :||                        |.||:||.:....|  |.|:..:||:..| |.    ..
Human   399 ALGTLGLEERVNRALALSRYLVDEIKKREGFKLLMEPEYANICFWYIPPSLREMEEGPE----FW 459

  Fly   366 SRFNSISLAITLATLAGDQMKSITKLGSMLHMRGVSGARVIVPGQNKTIDGHEFLDFGSHRSNLQ 430
            ::.|.::.||         .:.:.|.||::                        |.:..||..:.
Human   460 AKLNLVAPAI---------KERMMKKGSLM------------------------LGYQPHRGKVN 491

  Fly   431 VPYLTVAAGIGITREEIDKFFD 452
            . :..|.....::||::|...|
Human   492 F-FRQVVISPQVSREDMDFLLD 512

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
SecS	NP_649556.3	AAT_I	12..457	CDD:302748	52/282 (18%)
GADL1	NP_997242.2	AAT_I	77..445	CDD:302748	33/175 (19%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0076
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	1	0.900