Protein Alignment SecS and GAD1

DIOPT Version :9

• Sequence 1: NP_649556.3
• Gene: SecS / 40681
• FlyBaseID: FBgn0037347
• Length: 478
• Species: Drosophila melanogaster
• Sequence 2: NP_000808.2
• Gene: GAD1 / 2571
• HGNCID: 4092
• Length: 594
• Species: Homo sapiens
• Alignment Length: 217
• Identity: 48/217 - (22%)
• Similarity: 83/217 - (38%)
• Gaps: 50/217 - (23%)

  Fly   264 NQLECANRVGRIDYFVQ-SSDKNLLVPVGSAIVASFNESVLHDVASTYA-----GRASGSQSLDV 322
            |.||..:|:  :..|.: .|.||||....|...|.|..:.. |.::.:|     .:....|::..
Human    55 NSLEEKSRL--VSAFKERQSSKNLLSCENSDRDARFRRTET-DFSNLFARDLLPAKNGEEQTVQF 116

  Fly   323 LMTLLSLGRNGFRLLFDQRGENFNY-----LRENLRKF-------AEPRGEIVIDSR-------- 367
            |:.::.:..|..|..||:..:..::     |.|.:..|       .|...:|::|.|
Human   117 LLEVVDILLNYVRKTFDRSTKVLDFHHPHQLLEGMEGFNLELSDHPESLEQILVDCRDTLKYGVR 181

  Fly   368 ------FNSISLAITLATLAGDQMKS----------ITKLGSMLHMRGVSGARVIVPGQNKTIDG 416
                  ||.:|..:.:..|||:.:.|          |..:..::....:...|.||...:|  ||
Human   182 TGHPRFFNQLSTGLDIIGLAGEWLTSTANTNMFTYEIAPVFVLMEQITLKKMREIVGWSSK--DG 244

  Fly   417 HEFLDFGSHRSNLQVPYLTVAA 438
            ......|...||:   |..:||
Human   245 DGIFSPGGAISNM---YSIMAA 263

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
SecS	NP_649556.3	AAT_I	12..457	CDD:302748	48/217 (22%)
GAD1	NP_000808.2	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1..23
		Pyridoxal_deC	144..518	CDD:365998	27/125 (22%)
		Substrate binding	190..192		0/1 (0%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0076
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	1	0.900