DRSC/TRiP Functional Genomics Resources

powered by:
logo

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits


Protein Alignment SecS and Gad2

DIOPT Version :9

Sequence 1:NP_649556.3 Gene:SecS / 40681 FlyBaseID:FBgn0037347 Length:478 Species:Drosophila melanogaster
Sequence 2:NP_036695.1 Gene:Gad2 / 24380 RGDID:2653 Length:585 Species:Rattus norvegicus


Alignment Length:339 Identity:60/339 - (17%)
Similarity:124/339 - (36%) Gaps:97/339 - (28%)


- Green bases have known domain annotations that are detailed below.


  Fly   162 ARYVLWSRIDQK------------------SCFKAITATGL---VPVVIPCLIKGESLNTNVDLF 205
            |||.::..:.:|                  |..|...|.|:   ..::|.|..:|:.:.::::..
  Rat   254 ARYKMFPEVKEKGMAAVPRLIAFTSEHSHFSLKKGAAALGIGTDSVILIKCDERGKMIPSDLERR 318

  Fly   206 REKIKSLGVDSILCLYTT-TSCFAPRNSDDIAEVSKLSKQWQIPHLVNNAYG------LQAKEIV 263
            ..::|..|....|...|. |:.:..  .|.:..|:.:.|:::|...|:.|:|      .:.|..:
  Rat   319 ILEVKQKGFVPFLVSATAGTTVYGA--FDPLLAVADICKKYKIWMHVDAAWGGGLLMSRKHKWKL 381

  Fly   264 NQLECANRVGRIDYFVQSSDKNLLVPVGSAIVASFNESVLHDVASTYAG---------------- 312
            |.:|.||.|      ..:..|.:.||:..:.:....|.::......:|.                
  Rat   382 NGVERANSV------TWNPHKMMGVPLQCSALLVREEGLMQSCNQMHASYLFQQDKHYDLSYDTG 440

  Fly   313 -------------------RASGS--------QSLDVLMTLLSL--GRNGFRLLFDQRGENFN-- 346
                               ||.|:        :.|::...|.::  .|.|:.::||.:.::.|  
  Rat   441 DKALQCGRHVDVFKLWLMWRAKGTTGFEAHIDKCLELAEYLYNIIKNREGYEMVFDGKPQHTNVC 505

  Fly   347 --YLRENLRKFAEPRGEIVIDSRFNSISLAITLATLA-GDQMKSITKLGSMLHMRGVSGARVIVP 408
              ::..:||...:....:   ||.:.::..|....:. |..|.|...||..     |:..|:::.
  Rat   506 FWFVPPSLRVLEDNEERM---SRLSKVAPVIKARMMEYGTTMVSYQPLGDK-----VNFFRMVIS 562

  Fly   409 GQNKTIDGHEFLDF 422
            ....|   |:.:||
  Rat   563 NPAAT---HQDIDF 573

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
SecSNP_649556.3 AAT_I 12..457 CDD:302748 60/339 (18%)
Gad2NP_036695.1 Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 1..25
Pyridoxal_deC 138..509 CDD:278699 44/262 (17%)
Substrate binding. /evidence=ECO:0000250 181..183
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 1 0.900 - - E1_COG0076
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
10.900

Return to query results.
Submit another query.