DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment SecS and Gad1

DIOPT Version :9

Sequence 1:	NP_649556.3	Gene:	SecS / 40681	FlyBaseID:	FBgn0037347	Length:	478	Species:	Drosophila melanogaster
Sequence 2:	NP_058703.1	Gene:	Gad1 / 24379	RGDID:	2652	Length:	593	Species:	Rattus norvegicus

Alignment Length:	217	Identity:	47/217 - (21%)
Similarity:	83/217 - (38%)	Gaps:	50/217 - (23%)

- Green bases have known domain annotations that are detailed below.

  Fly   264 NQLECANRVGRIDYF-VQSSDKNLLVPVGSAIVASFNESVLHDVASTYA-----GRASGSQSLDV 322
            |.||..:|:  :..| .:.:.||||....|...|.|..:.. |.::.:|     .:....|::..
  Rat    54 NSLEEKSRL--VSAFRERQASKNLLSCENSDPGARFRRTET-DFSNLFAQDLLPAKNGEEQTVQF 115

  Fly   323 LMTLLSLGRNGFRLLFDQRGENFNY-----LRENLRKF-------AEPRGEIVIDSR-------- 367
            |:.::.:..|..|..||:..:..::     |.|.:..|       .|...:|::|.|
  Rat   116 LLEVVDILLNYVRKTFDRSTKVLDFHHPHQLLEGMEGFNLELSDHPESLEQILVDCRDTLKYGVR 180

  Fly   368 ------FNSISLAITLATLAGDQMKS----------ITKLGSMLHMRGVSGARVIVPGQNKTIDG 416
                  ||.:|..:.:..|||:.:.|          |..:..::....:...|.|:...||  ||
  Rat   181 TGHPRFFNQLSTGLDIIGLAGEWLTSTANTNMFTYEIAPVFVLMEQITLKKMREIIGWSNK--DG 243

  Fly   417 HEFLDFGSHRSNLQVPYLTVAA 438
            ......|...||:   |..:||
  Rat   244 DGIFSPGGAISNM---YSIMAA 262

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
SecS	NP_649556.3	AAT_I	12..457	CDD:302748	47/217 (22%)
Gad1	NP_058703.1	Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	1..22
		Pyridoxal_deC	143..517	CDD:395219	27/125 (22%)
		Substrate binding. /evidence=ECO:0000250	189..191		0/1 (0%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0076
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.900