DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment SecS and Ddc

DIOPT Version :9

Sequence 1:	NP_649556.3	Gene:	SecS / 40681	FlyBaseID:	FBgn0037347	Length:	478	Species:	Drosophila melanogaster
Sequence 2:	NP_001257781.1	Gene:	Ddc / 24311	RGDID:	2494	Length:	480	Species:	Rattus norvegicus

Alignment Length:	199	Identity:	46/199 - (23%)
Similarity:	69/199 - (34%)	Gaps:	59/199 - (29%)

- Green bases have known domain annotations that are detailed below.

  Fly   255 YGLQAKEIVNQLECANRVGRIDYFVQSSDKNLLVPVGSAIVASFN-----------ESVLHDVAS 308
            |.::|..:...||.....|.|.:||       :|.:|:....||:           |.|...:.:
  Rat   215 YSMRAAALREALERDKAAGLIPFFV-------VVTLGTTSCCSFDNLLEVGPICNQEGVWLHIDA 272

  Fly   309 TYAGRA----------SGSQSLDVLMTLLSLGRNGFRLL---FD----------QRGENFNYLRE 350
            .|||.|          :|.:..|      |...|..:.|   ||          ...|.||....
  Rat   273 AYAGSAFICPEFRYLLNGVEFAD------SFNFNPHKWLLVNFDCSAMWVKKRTDLTEAFNMDPV 331

  Fly   351 NLRKFAEPRGEIVIDSRFNSISLAITLATLAGDQMKSITKLGSMLHMRGVSGARVIVPGQNKTID 415
            .||...:..| ::.|.|...|.|        |.:.:|: |:..:..|.||.|.:..:....|.
  Rat   332 YLRHSHQDSG-LITDYRHWQIPL--------GRRFRSL-KMWFVFRMYGVKGLQAYIRKHVKL-- 384

  Fly   416 GHEF 419
            .|||
  Rat   385 SHEF 388

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
SecS	NP_649556.3	AAT_I	12..457	CDD:302748	46/199 (23%)
Ddc	NP_001257781.1	Pyridoxal_deC	35..414	CDD:278699	46/199 (23%)
Ddc	NP_001257781.1	2 X approximate tandem repeats	58..178
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0076
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.900