Protein Alignment SecS and Sgpl1

DIOPT Version :10

• Sequence 1: NP_649556.3
• Gene: SecS / 40681
• FlyBaseID: FBgn0037347
• Length: 478
• Species: Drosophila melanogaster
• Sequence 2: NP_033189.2
• Gene: Sgpl1 / 20397
• MGIID: 1261415
• Length: 568
• Species: Mus musculus
• Alignment Length: 525
• Identity: 103/525 - (19%)
• Similarity: 167/525 - (31%)
• Gaps: 206/525 - (39%)

  Fly     3 FEQVNIPEKLVPDNYLQLGLAAQRSKQRSFKELLEKRKLPKNGWSDERIEELVHMLASLDSNNYP 67
            :|.:..||.|           ..|.|::.||.:   ||:|..|   .:||:.|.........|.|
Mouse    57 YELIFQPESL-----------WSRFKKKLFKLI---RKMPFIG---RKIEQQVSKAKKDLVKNMP 104

  Fly    68 H-KV-----------GLGEREARIACKLVARRHYNFGHGIGR----SGDLLEAQPKAAGSTLLAR 116
            . ||           |:|..|.     |...:.|:...|..:    ||.:...:||.  :.||.:
Mouse   105 FLKVDKDYVKTLPAQGMGTAEV-----LERLKEYSSMDGSWQEGKASGAVYNGEPKL--TELLVQ 162

  Fly   117 L------TNALILDLIRGI----------------GLPSCAGCFLVPMCTGMTLTLCLQSLRKRR 159
            .      :|.|..|:..|:                |.|...||    :.:|.|.::.:
Mouse   163 AYGEFTWSNPLHPDIFPGLRKLEAEIVRMTCSLFNGGPDSCGC----VTSGGTESILM------- 216

  Fly   160 PGARYVLWSRIDQKSCFKAITATGLVP-VVIPCLIKGESLNTNVD----LFREKI------KSLG 213
                          :| ||.....|.. :..|.::..||.:...|    .|..||      |::.
Mouse   217 --------------AC-KAYRDLALEKGIKTPEIVAPESAHAAFDKAAHYFGMKIVRVALKKNME 266

  Fly   214 VD----------SILCLYTTTSCFAPRNSDDIAEVSKLSKQWQIPHLVNNAYGLQAKEIVNQLEC 268
            ||          :...|..:|..|.....|.:.||:||:.:::||..|:...|   ..::..:|.
Mouse   267 VDVQAMKRAISRNTAMLVCSTPQFPHGVMDPVPEVAKLAVRYKIPLHVDACLG---GFLIVFMEK 328

  Fly   269 AN---------RVGRIDYFVQSSDKNLLVPVGSAIVASFNE---SVLHDVASTYAGRASGSQSL- 320
            |.         ||..:......:.|....|.||::|...||   :....|.:.:.|....|.|:
Mouse   329 AGYPLEKPFDFRVKGVTSISADTHKYGYAPKGSSVVMYSNEKYRTYQFFVGADWQGGVYASPSIA 393

  Fly   321 ---------------------------------------------------DVLMTLLSLGRNGF 334
                                                               |..:::::||.|.|
Mouse   394 GSRPGGIIAACWAALMHFGENGYVEATKQIIKTARFLKSELENIKNIFIFGDPQLSVIALGSNDF 458

  Fly   335 RL-----LFDQRGENFNYLRENLRKFAEPRGEIVIDSRFNSISLAITLA--------TLAGDQMK 386
            .:     :...:|.|||||:       .||          ||...|||.        ....|..:
Mouse   459 DIYRLSNMMSAKGWNFNYLQ-------FPR----------SIHFCITLVHTRKRVAIQFLKDIRE 506

  Fly   387 SITKL 391
            |:|::
Mouse   507 SVTQI 511

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
SecS	NP_649556.3	AAT_I	12..457	CDD:450240	100/516 (19%)
Sgpl1	NP_033189.2	DOPA_deC_like	146..507	CDD:99743	76/408 (19%)