Protein Alignment SecS and DDC

DIOPT Version :9

• Sequence 1: NP_649556.3
• Gene: SecS / 40681
• FlyBaseID: FBgn0037347
• Length: 478
• Species: Drosophila melanogaster
• Sequence 2: NP_000781.2
• Gene: DDC / 1644
• HGNCID: 2719
• Length: 480
• Species: Homo sapiens
• Alignment Length: 259
• Identity: 56/259 - (21%)
• Similarity: 91/259 - (35%)
• Gaps: 83/259 - (32%)

  Fly   181 ATGLVPVVIPCLIKGESLNTNVDLFREKIKSLGVDSILCLYTTTSCFAPRNSDDIAEVSKLSKQW 245
            |.||:|..:                   :.:||        |||.|    :.|::.||..:..:.
Human   231 AAGLIPFFM-------------------VATLG--------TTTCC----SFDNLLEVGPICNKE 264

  Fly   246 QIPHLVNNAYGLQA------KEIVNQLECANRVGRIDYFVQSSDKNLLVPVGSAIVASFNESVLH 304
            .|...|:.||...|      :.::|.:|.|      |.|..:..|.|||        :|:.|.:.
Human   265 DIWLHVDAAYAGSAFICPEFRHLLNGVEFA------DSFNFNPHKWLLV--------NFDCSAMW 315

  Fly   305 DVASTYAGRASGSQSLDVLMTLLSLGRNGFRLLFDQR------GENFN----------------- 346
            ....|   ..:|:..||  .|.|........|:.|.|      |..|.
Human   316 VKKRT---DLTGAFRLD--PTYLKHSHQDSGLITDYRHWQIPLGRRFRSLKMWFVFRMYGVKGLQ 375

  Fly   347 -YLRENLRKFAEPRGEIVIDSRFNSISLAITLATLAGDQMKSITKLGSMLHMRGVSGARV-IVP 408
             |:|::::...|....:..|.|| .|.:.:.|. |...::|...|:...|..|..|..:: :||
Human   376 AYIRKHVQLSHEFESLVRQDPRF-EICVEVILG-LVCFRLKGSNKVNEALLQRINSAKKIHLVP 437

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
SecS	NP_649556.3	AAT_I	12..457	CDD:302748	56/259 (22%)
DDC	NP_000781.2	Pyridoxal_deC	35..414	CDD:365998	49/234 (21%)
		2 X approximate tandem repeats	58..178

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0076
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	1	0.900