Protein Alignment SecS and Hdc

DIOPT Version :10

• Sequence 1: NP_649556.3
• Gene: SecS / 40681
• FlyBaseID: FBgn0037347
• Length: 478
• Species: Drosophila melanogaster
• Sequence 2: XP_006498847.1
• Gene: Hdc / 15186
• MGIID: 96062
• Length: 681
• Species: Mus musculus
• Alignment Length: 333
• Identity: 60/333 - (18%)
• Similarity: 106/333 - (31%)
• Gaps: 112/333 - (33%)

  Fly   184 LVPVVIP-CLIKGESLNTN--------------VDLFREKIKSLGVDSIL------CLYTTTSCF 227
            |.|:..| ||.|.:.|:|.              ||...:.:.::....:.      .|.......
Mouse     8 LSPIPSPRCLPKRQPLSTTTLRVRCFILSGKEMVDYISQYLSTVRERQVTPNVQPGYLRAQLPAS 72

  Fly   228 APRNSD-------DIAEVSKLS-KQWQIPHLVNNAY--------GLQAKEIVNQLEC-------- 268
            ||...|       ||..|.... ..||.||:  :||        .|....:.:.:.|
Mouse    73 APEEPDSWDSIFGDIERVIMPGVVHWQSPHM--HAYYPALTSWPSLLGDMLADAINCLGFTWASS 135

  Fly   269 --------------ANRVGRIDYFVQ------------------------SSDKNLLVPVGSAIV 295
                          |..:|..:||:.                        ::.||.::.: .|..
Mouse   136 PACTELEMNIMDWLAKMLGLPEYFLHHHPSSRGGGVLQSTVSESTLIALLAARKNKILAM-KACE 199

  Fly   296 ASFNESVLHDVASTY-AGRASGSQSLDVLMTLLSLGRNGFRLLFDQRGENFNYLRENLRKFAE-- 357
            ...|||.|:.....| :.:|..|.....|::|:       ::.|....:||:...|.|:|..|
Mouse   200 PDANESSLNARLVAYTSDQAHSSVEKAGLISLV-------KIRFLPVDDNFSLRGEALQKAIEED 257

  Fly   358 -PRGEIVIDSRFNSISLAITLATLAGDQMKSITKLGSMLHMRGV--------SGARVIVPGQNKT 413
             .:|.:       .:.:..||.|........:::||.:....|:        :|...:.|.....
Mouse   258 KQQGLV-------PVFVCATLGTTGVCAFDRLSELGPICASEGLWLHVDAAYAGTAFLCPELRGF 315

  Fly   414 IDGHEFLD 421
            ::|.|:.|
Mouse   316 LEGIEYAD 323

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
SecS	NP_649556.3	AAT_I	12..457	CDD:450240	60/333 (18%)
Hdc	XP_006498847.1	Pyridoxal_deC	62..440	CDD:395219	50/279 (18%)