DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment kra and bzw1

DIOPT Version :9

Sequence 1:	NP_524238.1	Gene:	kra / 40680	FlyBaseID:	FBgn0250753	Length:	422	Species:	Drosophila melanogaster
Sequence 2:	NP_989281.1	Gene:	bzw1 / 394895	XenbaseID:	XB-GENE-5740554	Length:	419	Species:	Xenopus tropicalis

Alignment Length:	417	Identity:	221/417 - (52%)
Similarity:	315/417 - (75%)	Gaps:	2/417 - (0%)

- Green bases have known domain annotations that are detailed below.

  Fly     2 SQKTERPVLSGQRIKTRKRDEREKYDPTGFRDAVIAGLEKTEGDLEQISKYLDSAGNKLDYRRYG 66
            :||.::|.|||||.|||||||:|::|||.|:|.:|.||.:|..|||.::|:||::|.|||||||.
Frog     3 NQKQQKPTLSGQRFKTRKRDEKERFDPTQFQDCIIQGLNETGNDLEAVAKFLDASGAKLDYRRYA 67

  Fly    67 EVLFDILIAGGLLVPGGSISQDGEKPRTSYCIFDAPESMESMRNHEQVFVKLIRRYKYLEKMFEE 131
            |.|||||:|||:|.|||:::.  |..||..|:|.|.|.:|:|:...|||.|||||||||||.|||
Frog    68 ETLFDILVAGGMLAPGGTLAD--EVIRTDVCVFSAQEDLETMQAFAQVFNKLIRRYKYLEKGFEE 130

  Fly   132 EMGKVLLFVKGFTPSERIKLARMTALWLVNGSVPPNVLLVLNNEHLIKDGIALEFLLELFQTFKQ 196
            |:.|:|||:|||:.|||.|||.:|.:.|.||::..::|..|.||:|:|:|::..|.::||:::..
Frog   131 EVKKLLLFLKGFSESERNKLAMLTGILLANGNLSASILNSLYNENLVKEGVSAAFAVKLFKSWIN 195

  Fly   197 EKGIAYLIQALKKGGLESKLMDFFPPNKRTEEYFKQVFLDKELNEIVKLHKAQASQEAKRELQQA 261
            ||.|..:..:|:|..::::||:.||.||:|.|:|.:.|.|..|.|:.:..:.|.:..|::|||:.
Frog   196 EKDINAVAGSLRKVNMDNRLMELFPANKQTVEHFTKYFTDAGLKELAEYVRNQQTIGARKELQKE 260

  Fly   262 LIDDINDEKPYNEITSDIKDFSQRTNIPDHEIIVIIWSTIMSLGEWNKKEELVTDQAVRHLKNYC 326
            |.:.::..:|..||:..:||..::.||.:..:|.|:||::||..||||||||||:||::|||.|.
Frog   261 LQEMMSRGEPLKEISMYVKDEMKKNNISEQTVIGILWSSVMSCVEWNKKEELVTEQAIKHLKQYS 325

  Fly   327 PLLQAFASTDRSELALILKVQEFCYENMNFMKAFQKIILLFYKTEVLSEEIILRWYKEGHSNKGK 391
            |||.||.:..:|||.|:||:||:||:|::|||:||||::||||.||||||.||:|||:.|..|||
Frog   326 PLLAAFTTQGQSELTLLLKIQEYCYDNIHFMKSFQKIVVLFYKAEVLSEEPILKWYKDAHLAKGK 390

  Fly   392 MHFLEQMRKFVEWLQSAEEESESEDEQ 418
            ..|||||:||||||::||||||||.|:
Frog   391 SVFLEQMKKFVEWLKNAEEESESETEE 417

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
kra	NP_524238.1	W2_eIF5C_like	218..406	CDD:211398	98/187 (52%)
bzw1	NP_989281.1	Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	1..26		15/22 (68%)
bzw1	NP_989281.1	W2_eIF5C_like	217..407	CDD:211398	99/189 (52%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	335	1.000	Domainoid score	I1135
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H41651
Inparanoid	1	1.050	455	1.000	Inparanoid score	I1543
OMA	1	1.010	-	-		QHG57232
OrthoDB	1	1.010	-	-		D383363at33208
OrthoFinder	1	1.000	-	-		FOG0002614
OrthoInspector	1	1.000	-	-		otm47828
Panther	1	1.100	-	-	O	PTHR14208
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R4560
SonicParanoid	1	1.000	-	-		X1719
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	13	13.110