Protein Alignment kra and BZW2

DIOPT Version :9

• Sequence 1: NP_524238.1
• Gene: kra / 40680
• FlyBaseID: FBgn0250753
• Length: 422
• Species: Drosophila melanogaster
• Sequence 2: NP_001153239.1
• Gene: BZW2 / 28969
• HGNCID: 18808
• Length: 419
• Species: Homo sapiens
• Alignment Length: 416
• Identity: 209/416 - (50%)
• Similarity: 305/416 - (73%)
• Gaps: 1/416 - (0%)

  Fly     4 KTERPVLSGQRIKTRKRDEREKYDPTGFRDAVIAGLEKTEGDLEQISKYLDSAGNKLDYRRYGEV 68
            |.::|||:|||.|||||||:||::||.|||.::.||.:...|||.::|:|||.|::||||||.:.
Human     3 KHQKPVLTGQRFKTRKRDEKEKFEPTVFRDTLVQGLNEAGDDLEAVAKFLDSTGSRLDYRRYADT 67

  Fly    69 LFDILIAGGLLVPGGSISQDGEKPR-TSYCIFDAPESMESMRNHEQVFVKLIRRYKYLEKMFEEE 132
            |||||:||.:|.|||:...||:|.: |::|:|.|.|..|::||:.|||.|||||||||||.||:|
Human    68 LFDILVAGSMLAPGGTRIDDGDKTKMTNHCVFSANEDHETIRNYAQVFNKLIRRYKYLEKAFEDE 132

  Fly   133 MGKVLLFVKGFTPSERIKLARMTALWLVNGSVPPNVLLVLNNEHLIKDGIALEFLLELFQTFKQE 197
            |.|:|||:|.|:.:|:.|||.::.:.|.||::|..:|..|..:.|:|:|||..|.::||:.:..|
Human   133 MKKLLLFLKAFSETEQTKLAMLSGILLGNGTLPATILTSLFTDSLVKEGIAASFAVKLFKAWMAE 197

  Fly   198 KGIAYLIQALKKGGLESKLMDFFPPNKRTEEYFKQVFLDKELNEIVKLHKAQASQEAKRELQQAL 262
            |....:..:|:|..|:.:|::.||.|:::.::|.:.|.|..|.|:....:.|.|...::|||:.|
Human   198 KDANSVTSSLRKANLDKRLLELFPVNRQSVDHFAKYFTDAGLKELSDFLRVQQSLGTRKELQKEL 262

  Fly   263 IDDINDEKPYNEITSDIKDFSQRTNIPDHEIIVIIWSTIMSLGEWNKKEELVTDQAVRHLKNYCP 327
            .:.::.|.|..|:...:|:..:|.::|:..:|.::|:.||:..|||||||||.:||::|||.|.|
Human   263 QERLSQECPIKEVVLYVKEEMKRNDLPETAVIGLLWTCIMNAVEWNKKEELVAEQALKHLKQYAP 327

  Fly   328 LLQAFASTDRSELALILKVQEFCYENMNFMKAFQKIILLFYKTEVLSEEIILRWYKEGHSNKGKM 392
            ||..|:|..:|||.|:.||||:||:|::||||||||::||||.:|||||.||:||||.|..|||.
Human   328 LLAVFSSQGQSELILLQKVQEYCYDNIHFMKAFQKIVVLFYKADVLSEEAILKWYKEAHVAKGKS 392

  Fly   393 HFLEQMRKFVEWLQSAEEESESEDEQ 418
            .||:||:|||||||:||||||||.|:
Human   393 VFLDQMKKFVEWLQNAEEESESEGEE 418

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
kra	NP_524238.1	W2_eIF5C_like	218..406	CDD:211398	91/187 (49%)
BZW2	NP_001153239.1	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1..22		13/18 (72%)
		W2_eIF5C_like	218..408	CDD:211398	93/189 (49%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C165150897
Domainoid	1	1.000	327	1.000	Domainoid score	I1172
eggNOG	1	0.900	-	-		E1_KOG2297
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	448	1.000	Inparanoid score	I1627
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG57232
OrthoDB	1	1.010	-	-		D383363at33208
OrthoFinder	1	1.000	-	-		FOG0002614
OrthoInspector	1	1.000	-	-		otm40652
orthoMCL	1	0.900	-	-		OOG6_103948
Panther	1	1.100	-	-	LDO	PTHR14208
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X1719
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
User_Submission	0	0.000	Not matched by this tool.
	14	13.770