Protein Alignment kra and EIF5

DIOPT Version :9

• Sequence 1: NP_524238.1
• Gene: kra / 40680
• FlyBaseID: FBgn0250753
• Length: 422
• Species: Drosophila melanogaster
• Sequence 2: NP_001960.2
• Gene: EIF5 / 1983
• HGNCID: 3299
• Length: 431
• Species: Homo sapiens
• Alignment Length: 391
• Identity: 88/391 - (22%)
• Similarity: 143/391 - (36%)
• Gaps: 104/391 - (26%)

  Fly   110 NHEQVFVKLIRRYKYLEKMFEEEMGKVLLF-VKGFTPSERIKLARMTALWLVNGSVPPNVLLVLN 173
            |...|...|.|...|..|.|..|:|....| ||    ::|         ::||||...|.|
Human    38 NMVDVAKALNRPPTYPTKYFGCELGAQTQFDVK----NDR---------YIVNGSHEANKL---- 85

  Fly   174 NEHLIKDGIALEFLL---------ELFQTFKQE------KGIAYLIQALKKGGLES--KLMDFF- 220
             :.:: ||...:|:|         :|....|::      |...|      :|.|::  ||..|.
Human    86 -QDML-DGFIKKFVLCPECENPETDLHVNPKKQTIGNSCKACGY------RGMLDTHHKLCTFIL 142

  Fly   221 --PP-------NKRTEEYFKQVFLDKE---------------LNEIVKLHKAQASQE-------A 254
              ||       .|:.:|...:...|||               .|||.........:|       .
Human   143 KNPPENSDSGTGKKEKEKKNRKGKDKENGSVSSSETPPPPPPPNEINPPPHTMEEEEDDDWGEDT 207

  Fly   255 KRELQQALIDDINDEKPYNEITSDI-KDFSQRTNI----------------PDHEIIVIIWS-TI 301
            ..|.|:..:|:|:|......::.|: :...:|.||                .|.||:..... .:
Human   208 TEEAQRRRMDEISDHAKVLTLSDDLERTIEERVNILFDFVKKKKEEGVIDSSDKEIVAEAERLDV 272

  Fly   302 MSLGEWNKKEELVTDQAVRHLKNYCPLLQAFASTDRSELALILKVQEFCYENMNFMKAFQK---I 363
            .::|.....|.|..::....:|.|......|...::.....:|...| |...|:..:...|   |
Human   273 KAMGPLVLTEVLFNEKIREQIKKYRRHFLRFCHNNKKAQRYLLHGLE-CVVAMHQAQLISKIPHI 336

  Fly   364 ILLFYKTEVLSEEIILRWYKEGHSNKGKMHFLEQMR----KFVEWLQSAEEES---ESEDEQKNG 421
            :...|..::|.||:|:.|.::...........:::|    .|::||:.|||||   |.|||.:|.
Human   337 LKEMYDADLLEEEVIISWSEKASKKYVSKELAKEIRVKAEPFIKWLKEAEEESSGGEEEDEDENI 401

  Fly   422 E 422
            |
Human   402 E 402

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
kra	NP_524238.1	W2_eIF5C_like	218..406	CDD:211398	45/244 (18%)
EIF5	NP_001960.2	eIF-5_eIF-2B	9..128	CDD:280114	27/114 (24%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	143..216		13/72 (18%)
		W2_eIF5	233..385	CDD:211399	28/152 (18%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	1	0.950	-	0	Normalized mean entropy	S1073
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	1	0.950