DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment kra and C37C3.2

DIOPT Version :9

Sequence 1:	NP_524238.1	Gene:	kra / 40680	FlyBaseID:	FBgn0250753	Length:	422	Species:	Drosophila melanogaster
Sequence 2:	NP_001370553.1	Gene:	C37C3.2 / 179165	WormBaseID:	WBGene00016496	Length:	436	Species:	Caenorhabditis elegans

Alignment Length:	210	Identity:	42/210 - (20%)
Similarity:	88/210 - (41%)	Gaps:	36/210 - (17%)

- Green bases have known domain annotations that are detailed below.

  Fly   222 PNKRTEEYFKQVFLDKELNEIVKLHKAQASQEAKRELQQALI------DDINDEKPYNEITSDIK 280
            ||........::.|||:|         :.|:|.:.::.....      |.|:|.|.    .:.::
Worm   198 PNGMLSAGMGKLVLDKDL---------EKSEEQRLDMLHTFFLKAKEEDRISDAKG----QTALR 249

  Fly   281 DFSQRTNIPDHEIIVIIWSTIMSLGEWNKKEELVTDQAVRHLKNYCPLLQAFASTD-RSELALIL 344
            |.::|..:.....::        |......|:::||:.:...:|   ||..|...| :::..|:.
Worm   250 DEAERLELKQKASLL--------LANVFLDEKVITDKQISKHRN---LLLRFTLNDKKAQRYLLG 303

  Fly   345 KVQEFCYEN-MNFMKAFQKIILLFYKTEVLSEEIILRWYKEGHSNKGKMHF----LEQMRKFVEW 404
            .|::..::: ...:.....||...|..:|..|:.::.|.::..|......|    :|..:..:.|
Worm   304 GVEQVIHKHEAELLSKSAHIIKSLYDEDVCEEDSLISWGEKPSSKYVSKSFAKKIIENSQPVLNW 368

  Fly   405 LQSAEEESESEDEQK 419
            |:.||||:|.|.:.:
Worm   369 LKEAEEETEEESDDE 383

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
kra	NP_524238.1	W2_eIF5C_like	218..406	CDD:211398	35/195 (18%)
C37C3.2	NP_001370553.1	eIF-5_eIF-2B	9..126	CDD:396445
C37C3.2	NP_001370553.1	W2_eIF5	216..370	CDD:211399	29/168 (17%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	1	0.950	-	0	Normalized mean entropy	S1073
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.950