DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Vha26 and Atp6v1e2

DIOPT Version :9

Sequence 1:	NP_001287182.1	Gene:	Vha26 / 40679	FlyBaseID:	FBgn0283535	Length:	226	Species:	Drosophila melanogaster
Sequence 2:	NP_083397.3	Gene:	Atp6v1e2 / 74915	MGIID:	1922165	Length:	226	Species:	Mus musculus

Alignment Length:	224	Identity:	126/224 - (56%)
Similarity:	170/224 - (75%)	Gaps:	0/224 - (0%)

- Green bases have known domain annotations that are detailed below.

  Fly     1 MALSDADVQKQIKHMMAFIEQEANEKAEEIDAKAEEEFNIEKGRLVQQQRLKIMEYYEKKEKQVE 65
            |||:|.|||||||||||||||||||||||||||||||||||||||||.||||||:|:||||||:|
Mouse     1 MALTDIDVQKQIKHMMAFIEQEANEKAEEIDAKAEEEFNIEKGRLVQTQRLKIMDYFEKKEKQIE 65

  Fly    66 LQKKIQSSNMLNQARLKVLKVREDHVSSVLDDARKRLGEVTKNQSEYETVLTKLIVQGLFQIMEP 130
            .|||||.|.|.||||:.||:.|::.:..:|.||:.||..:..::..|:.:|.||::|.|.:::||
Mouse    66 QQKKIQLSTMRNQARITVLRARDNLILELLKDAKMRLSRIVSDEEIYQDLLDKLVLQALLRLLEP 130

  Fly   131 KVILRCREVDVPLVRNVLPAAVEQYKAQINQNVELFIDEKDFLSADTCGGVELLALNGRIKVPNT 195
            .:|:|||..|:.||.:.:..|:.||.....:::|:.:|:.:.|.::..||||:.:.:.:|||.||
Mouse   131 VMIVRCRPQDLHLVESAVLRAIPQYMRLCQKHLEVQVDQTEHLPSNAAGGVEVYSSDQKIKVSNT 195

  Fly   196 LESRLDLISQQLVPEIRNALFGRNVNRKF 224
            |||||:|.:.|.:||||..|||.|.:|||
Mouse   196 LESRLNLAAMQKMPEIRGILFGDNTSRKF 224

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Vha26	NP_001287182.1	NtpE	9..217	CDD:224308	114/207 (55%)
Vha26	NP_001287182.1	vATP-synt_E	18..216	CDD:280215	104/197 (53%)
Atp6v1e2	NP_083397.3	vATP-synt_E	18..216	CDD:396537	104/197 (53%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C167838255
Domainoid	1	1.000	243	1.000	Domainoid score	I2202
eggNOG	1	0.900	-	-		E1_COG1390
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	290	1.000	Inparanoid score	I2783
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG53684
OrthoDB	1	1.010	-	-		D1489718at2759
OrthoFinder	1	1.000	-	-		FOG0002151
OrthoInspector	1	1.000	-	-		otm44025
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR45715
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R1632
SonicParanoid	1	1.000	-	-		X1613
SwiftOrtho	1	1.000	-	-
TreeFam	1	0.960	-	-
	15	14.900