DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Vha26 and Atp6v1e2

DIOPT Version :9

Sequence 1:	NP_001287182.1	Gene:	Vha26 / 40679	FlyBaseID:	FBgn0283535	Length:	226	Species:	Drosophila melanogaster
Sequence 2:	NP_001102449.1	Gene:	Atp6v1e2 / 366545	RGDID:	1311680	Length:	226	Species:	Rattus norvegicus

Alignment Length:	224	Identity:	130/224 - (58%)
Similarity:	173/224 - (77%)	Gaps:	0/224 - (0%)

- Green bases have known domain annotations that are detailed below.

  Fly     1 MALSDADVQKQIKHMMAFIEQEANEKAEEIDAKAEEEFNIEKGRLVQQQRLKIMEYYEKKEKQVE 65
            |||:|.|||||||||||||||||||||||||||||||||||||||||.||||||:|:||||||:|
  Rat     1 MALTDIDVQKQIKHMMAFIEQEANEKAEEIDAKAEEEFNIEKGRLVQTQRLKIMDYFEKKEKQIE 65

  Fly    66 LQKKIQSSNMLNQARLKVLKVREDHVSSVLDDARKRLGEVTKNQSEYETVLTKLIVQGLFQIMEP 130
            .|||||.|.|.||||:.||:.|::.:..:|.:|:.||..:..::..|:.:|.||::|.|.:::||
  Rat    66 QQKKIQLSTMRNQARITVLRARDNLILELLKEAKMRLSRIVSDEEFYQDLLDKLVLQALLRLLEP 130

  Fly   131 KVILRCREVDVPLVRNVLPAAVEQYKAQINQNVELFIDEKDFLSADTCGGVELLALNGRIKVPNT 195
            .:|:||||.|..||::.|..|:.||.....:::|:.||:.::||::..||||:.:.:.:|||.||
  Rat   131 VMIVRCREQDFYLVQSALLRAIPQYMMLCQKHLEVQIDQTEYLSSNAAGGVEVYSSDRKIKVSNT 195

  Fly   196 LESRLDLISQQLVPEIRNALFGRNVNRKF 224
            |||||:|.:.|.:||||..|||.|.||||
  Rat   196 LESRLNLAALQNMPEIRRTLFGDNSNRKF 224

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Vha26	NP_001287182.1	NtpE	9..217	CDD:224308	117/207 (57%)
Vha26	NP_001287182.1	vATP-synt_E	18..216	CDD:280215	107/197 (54%)
Atp6v1e2	NP_001102449.1	NtpE	9..217	CDD:224308	117/207 (57%)
Atp6v1e2	NP_001102449.1	vATP-synt_E	18..216	CDD:280215	107/197 (54%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C166342031
Domainoid	1	1.000	243	1.000	Domainoid score	I2140
eggNOG	1	0.900	-	-		E1_COG1390
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	289	1.000	Inparanoid score	I2725
OMA	1	1.010	-	-		QHG53684
OrthoDB	1	1.010	-	-		D1489718at2759
OrthoFinder	1	1.000	-	-		FOG0002151
OrthoInspector	1	1.000	-	-		otm46116
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR45715
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X1613
SwiftOrtho	1	1.000	-	-
TreeFam	1	0.960	-	-
	14	13.870