DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Vha26 and vha-8

DIOPT Version :9

Sequence 1:	NP_001287182.1	Gene:	Vha26 / 40679	FlyBaseID:	FBgn0283535	Length:	226	Species:	Drosophila melanogaster
Sequence 2:	NP_501040.1	Gene:	vha-8 / 177442	WormBaseID:	WBGene00006917	Length:	226	Species:	Caenorhabditis elegans

Alignment Length:	226	Identity:	133/226 - (58%)
Similarity:	177/226 - (78%)	Gaps:	0/226 - (0%)

- Green bases have known domain annotations that are detailed below.

  Fly     1 MALSDADVQKQIKHMMAFIEQEANEKAEEIDAKAEEEFNIEKGRLVQQQRLKIMEYYEKKEKQVE 65
            |.:||.|||||::|||||||||||||||||||||||||||||||||||||.||||::||||||||
Worm     1 MGISDNDVQKQLRHMMAFIEQEANEKAEEIDAKAEEEFNIEKGRLVQQQRQKIMEFFEKKEKQVE 65

  Fly    66 LQKKIQSSNMLNQARLKVLKVREDHVSSVLDDARKRLGEVTKNQSEYETVLTKLIVQGLFQIMEP 130
            ||:|||:||.||..||:.||.||||:.:|||:||..|..::.:.:.|..:|..|::|||.|::|.
Worm    66 LQRKIQASNSLNAGRLRCLKAREDHIGAVLDEARSNLSRISGDAARYPAILKGLVMQGLLQLLEK 130

  Fly   131 KVILRCREVDVPLVRNVLPAAVEQYKAQINQNVELFIDEKDFLSADTCGGVELLALNGRIKVPNT 195
            :|:|||||.|:.||..:||..::..:.:.....::.:|:::||.:::.|||||.|..|:|||.:|
Worm   131 EVVLRCREKDLRLVEQLLPECLDGLQKEWGSTTKVVLDKQNFLPSESAGGVELSARAGKIKVSST 195

  Fly   196 LESRLDLISQQLVPEIRNALFGRNVNRKFTD 226
            |||||:||:.|:||::|.||||.|.||.|.|
Worm   196 LESRLELIANQIVPQVRTALFGPNPNRSFFD 226

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Vha26	NP_001287182.1	NtpE	9..217	CDD:224308	121/207 (58%)
Vha26	NP_001287182.1	vATP-synt_E	18..216	CDD:280215	113/197 (57%)
vha-8	NP_501040.1	NtpE	9..218	CDD:224308	122/208 (59%)
vha-8	NP_501040.1	vATP-synt_E	18..216	CDD:280215	113/197 (57%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C160160069
Domainoid	1	1.000	235	1.000	Domainoid score	I1326
eggNOG	1	0.900	-	-		E1_COG1390
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H1282
Inparanoid	1	1.050	272	1.000	Inparanoid score	I1815
Isobase	1	0.950	-	0	Normalized mean entropy	S881
OMA	1	1.010	-	-		QHG53684
OrthoDB	1	1.010	-	-		D1489718at2759
OrthoFinder	1	1.000	-	-		FOG0002151
OrthoInspector	1	1.000	-	-		oto17678
orthoMCL	1	0.900	-	-		OOG6_101237
Panther	1	1.100	-	-	LDO	PTHR45715
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R1632
SonicParanoid	1	1.000	-	-		X1613
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	16	15.790