DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Vha26 and Atp6v1e1

DIOPT Version :9

Sequence 1:	NP_001287182.1	Gene:	Vha26 / 40679	FlyBaseID:	FBgn0283535	Length:	226	Species:	Drosophila melanogaster
Sequence 2:	NP_031536.2	Gene:	Atp6v1e1 / 11973	MGIID:	894326	Length:	226	Species:	Mus musculus

Alignment Length:	226	Identity:	142/226 - (62%)
Similarity:	186/226 - (82%)	Gaps:	0/226 - (0%)

- Green bases have known domain annotations that are detailed below.

  Fly     1 MALSDADVQKQIKHMMAFIEQEANEKAEEIDAKAEEEFNIEKGRLVQQQRLKIMEYYEKKEKQVE 65
            |||||||||||||||||||||||||||||||||||||||||||||||.|||||||||||||||:|
Mouse     1 MALSDADVQKQIKHMMAFIEQEANEKAEEIDAKAEEEFNIEKGRLVQTQRLKIMEYYEKKEKQIE 65

  Fly    66 LQKKIQSSNMLNQARLKVLKVREDHVSSVLDDARKRLGEVTKNQSEYETVLTKLIVQGLFQIMEP 130
            .|||||.||::||||||||:.|:|.::.:|::|::||.:|.|:.:.|:.:|..|::|||:|::||
Mouse    66 QQKKIQMSNLMNQARLKVLRARDDLITDLLNEAKQRLSKVVKDTTRYQVLLDGLVLQGLYQLLEP 130

  Fly   131 KVILRCREVDVPLVRNVLPAAVEQYKAQINQNVELFIDEKDFLSADTCGGVELLALNGRIKVPNT 195
            ::|:|||:.|.|||:..:..|:..||....::|::.||::.:|..:..||||:...:.:|||.||
Mouse   131 RMIVRCRKQDFPLVKAAVQKAIPMYKIATKKDVDVQIDQEAYLPEEIAGGVEIYNGDRKIKVSNT 195

  Fly   196 LESRLDLISQQLVPEIRNALFGRNVNRKFTD 226
            ||||||||:||::||:|.||||.|.||||.|
Mouse   196 LESRLDLIAQQMMPEVRGALFGANANRKFLD 226

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Vha26	NP_001287182.1	NtpE	9..217	CDD:224308	126/207 (61%)
Vha26	NP_001287182.1	vATP-synt_E	18..216	CDD:280215	116/197 (59%)
Atp6v1e1	NP_031536.2	vATP-synt_E	18..216	CDD:396537	116/197 (59%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C167838254
Domainoid	1	1.000	243	1.000	Domainoid score	I2202
eggNOG	1	0.900	-	-		E1_COG1390
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H1282
Inparanoid	1	1.050	290	1.000	Inparanoid score	I2783
Isobase	1	0.950	-	0	Normalized mean entropy	S881
OMA	1	1.010	-	-		QHG53684
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0002151
OrthoInspector	1	1.000	-	-		otm44025
orthoMCL	1	0.900	-	-		OOG6_101237
Panther	1	1.100	-	-	LDO	PTHR45715
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R1632
SonicParanoid	1	1.000	-	-		X1613
SwiftOrtho	1	1.000	-	-
TreeFam	1	0.960	-	-
	17	16.740