Protein Alignment noi and PRP9

DIOPT Version :9

• Sequence 1: NP_477114.1
• Gene: noi / 40678
• FlyBaseID: FBgn0014366
• Length: 503
• Species: Drosophila melanogaster
• Sequence 2: NP_010254.1
• Gene: PRP9 / 851531
• SGDID: S000002188
• Length: 530
• Species: Saccharomyces cerevisiae
• Alignment Length: 589
• Identity: 142/589 - (24%)
• Similarity: 242/589 - (41%)
• Gaps: 150/589 - (25%)

  Fly     4 LLEQQRRLHEERERLVKLMVDEHATKKP-------GEKERIHSEHRL------------------ 43
            |||.:|.|.||.| :::..:.|...:.|       .|..::..:.:|
Yeast     3 LLETRRSLLEEME-IIENAIAERIQRNPELYYHYIQESSKVFPDTKLPRSSLIAENKIYKFKKVK 66

  Fly    44 ---KYLMELHHNSTSQLRDLYEDKDNERKAEIAALSGPNEFNE-------FYARLKQIKQFYKSH 98
               |.::...|.....|||..|.:....|     ::.|.|..|       |..:|:|:::..|:.
Yeast    67 RKRKQIILQQHEINIFLRDYQEKQQTFNK-----INRPEETQEDDKDLPNFERKLQQLEKELKNE 126

  Fly    99 PAEVSVPLSVEFDEMIRVYNNPD-------------DMSALVEFTDEEGGGRYLDLNECYELYLN 150
            .....:.::.:.|:.....::.|             |:.....||.:|..|.|::|.:.:.|:||
Yeast   127 DENFELDINSKKDKYALFSSSSDPSRRTNILSDRARDLDLNEIFTRDEQYGEYMELEQFHSLWLN 191

  Fly   151 L------RSVEKLDYI-TYLMSFDHVFDIPRERKNREYRIYIETLNDYLHHFILRIQPLLDLEGE 208
            :      ..::.||.: .:|....::...|.:|||..|..::..|:.|:..|..:...|||....
Yeast   192 VIKRGDCSLLQFLDILELFLDDEKYLLTPPMDRKNDRYMAFLLKLSKYVETFFFKSYALLDAAAV 256

  Fly   209 LLKVELDFQRQWLMGTFPGFSIKETESALANTGAHLDLSAFSSWEELASLGLDRLKSALVALGLK 273
            ...::.||:..:..|:                                      |:|.  |.|:.
Yeast   257 ENLIKSDFEHSYCRGS--------------------------------------LRSE--AKGIY 281

  Fly   274 CGGTLEERAQRLFSTKGKSTLDPALMAKKPSAKTASAQSREHERHKEIAQLEALLYKYADLLSEQ 338
            |     ....|.|.|  .|..:..|:.|        ...:...:.:.....|..|::|...|:::
Yeast   282 C-----PFCSRWFKT--SSVFESHLVGK--------IHKKNESKRRNFVYSEYKLHRYLKYLNDE 331

  Fly   339 RAATKENVQRKQARTGGER-DDSDV-----EASESDNEDDPDADDVPYNPK-------------- 383
            .:.|:..|:||.|.|..|| .:.|:     ||...|:.:...|:.|....:
Yeast   332 FSRTRSFVERKLAFTANERMAEMDILTQKYEAPAYDSTEKEGAEQVDGEQRDGQLQEEHLSGKSF 396

  Fly   384 NLPLGWDGKPIPYWLYKLHGLNISYNCEICGNFTYKGPKAFQRHFAEWRHAHGMRCLGIPNTAHF 448
            ::|||.||.|:||||||||||:..|.||||.|..|.|.:.|:|||.|.||.:.:|||||..::.|
Yeast   397 DMPLGPDGLPMPYWLYKLHGLDREYRCEICSNKVYNGRRTFERHFNEERHIYHLRCLGIEPSSVF 461

  Fly   449 ANVTQIEDAITLWEKLKSQKQSERWVA--------------DQEEEFEDSLGNVVNRKTFEDLKR 499
            ..:|:|::|..||:.::.|.|.....|              :.|.|.||..|||:::|.:::||:
Yeast   462 KGITKIKEAQELWKNMQGQSQLTSIAAVPPKPNPSQLKVPTELELEEEDEEGNVMSKKVYDELKK 526

  Fly   500 QGLL 503
            |||:
Yeast   527 QGLV 530

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
noi	NP_477114.1	PRP9	2..503	CDD:227515	141/587 (24%)
		SF3a60_bindingd	74..99	CDD:288924	7/31 (23%)
		SF3A3	128..203	CDD:293442	20/81 (25%)
		Telomere_Sde2_2	244..301	CDD:290036	10/56 (18%)
		DUF3449	324..500	CDD:288759	73/209 (35%)
PRP9	NP_010254.1	PRP9	1..530	CDD:227515	141/587 (24%)
		C2H2 Zn finger	282..304	CDD:275371	7/36 (19%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C157342053
Domainoid	1	1.000	131	1.000	Domainoid score	I1127
eggNOG	1	0.900	-	-		E1_COG5188
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	146	1.000	Inparanoid score	I1148
Isobase	1	0.950	-	0	Normalized mean entropy	S1285
OMA	1	1.010	-	-		QHG54569
OrthoFinder	1	1.000	-	-		FOG0005236
OrthoInspector	1	1.000	-	-		oto99646
orthoMCL	1	0.900	-	-		OOG6_102364
Panther	1	1.100	-	-	LDO	PTHR12786
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R1285
SonicParanoid	1	1.000	-	-		X3755
TreeFam	1	0.960	-	-
	15	14.740