DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment noi and pcp1

DIOPT Version :9

Sequence 1:	NP_477114.1	Gene:	noi / 40678	FlyBaseID:	FBgn0014366	Length:	503	Species:	Drosophila melanogaster
Sequence 2:	NP_594115.1	Gene:	pcp1 / 2541455	PomBaseID:	SPAC6G9.06c	Length:	1208	Species:	Schizosaccharomyces pombe

Alignment Length:	376	Identity:	81/376 - (21%)
Similarity:	146/376 - (38%)	Gaps:	84/376 - (22%)

- Green bases have known domain annotations that are detailed below.

  Fly     1 METLLEQQRRLHEERERLVKLMVDEHATKKPGEKERIHSEHRLKYLMELHHNSTSQLRDLYEDKD 65
            :|:|..|.|.:.||:..| :|:..:::.|...| ..|..:...|.|..|...:::.|.::::.::
pombe   465 IESLRTQNREIDEEKNHL-RLLASKNSDKALAE-TNIRLQEVTKELETLRMKNSNDLNEIHDLRE 527

  Fly    66 NERKAEIAALSGPNEFNEFYARLKQIKQFYKSHPAEVSVPLSVEFDEMIRVYNNP--------DD 122
            ......:...|...|.:..   :.:::|..||:...||     |.:..|..|.|.        ::
pombe   528 ENEGLTLKIDSITKEKDRL---INELEQRIKSYEVNVS-----ELNGTIDEYRNKLKDKEETYNE 584

  Fly   123 MSALVEFTDEEGGGRYLDLNECYELYLNLRSVEKLDYITYLMSFDHVFDIPRE-----RKNRE-Y 181
            :....::.|.       ||...:|....|:..|| :..:.|...:.|....||     .|.|| .
pombe   585 VMNAFQYKDN-------DLRRFHESINKLQDREK-ELTSNLEKKNLVISSLRETVAMLEKERESI 641

  Fly   182 RIYI-------------ETLNDYLHHFILRIQPLLDLEGELLKVELDFQRQWLMGTFPGFSIKET 233
            :.|:             |.|||.:.  :|:.| |.|::.||                 ..|.:|.
pombe   642 KKYLSGNAKDLDNTNLMEILNDKIS--VLQRQ-LTDVKDEL-----------------DVSEEER 686

  Fly   234 ESALANTGAHLDLS--AFSSWEELASLGLDRLKSALVALGLKCGGTLEERAQRLFSTKGKSTLDP 296
            |.|:. .|..|..|  ..|:.::...|....||:.|:    .....|:.|.:.|      |.|..
pombe   687 EEAIV-AGQKLSASFELMSNEKQALELKYSSLKNELI----NAQNLLDRREEEL------SELSK 740

  Fly   297 ALMAKKPSAKTASAQSREHERHKEIAQLEALLYKYADLLSEQRAATKENVQ 347
            .|..::   |..|..:.:.|::|||..|.:.|   ||.|::.|....:.::
pombe   741 KLFEER---KIRSGSNDDIEKNKEINVLNSEL---ADKLAQIRHLESDKME 785

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
noi	NP_477114.1	PRP9	2..503	CDD:227515	81/375 (22%)
		SF3a60_bindingd	74..99	CDD:288924	5/24 (21%)
		SF3A3	128..203	CDD:293442	21/93 (23%)
		Telomere_Sde2_2	244..301	CDD:290036	13/58 (22%)
		DUF3449	324..500	CDD:288759	6/24 (25%)
pcp1	NP_594115.1	Smc	150..1010	CDD:224117	81/376 (22%)
		Cnn_1N	152..219	CDD:285263
		V_ATPase_I	545..>636	CDD:279793	20/106 (19%)
		DUF342	<928..1017	CDD:302792
		PACT_coil_coil	1112..1186	CDD:287467
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	0	0.000