Protein Alignment Rev7 and Mad2l2

DIOPT Version :9

• Sequence 1: NP_649555.1
• Gene: Rev7 / 40677
• FlyBaseID: FBgn0037345
• Length: 198
• Species: Drosophila melanogaster
• Sequence 2: NP_001292349.1
• Gene: Mad2l2 / 71890
• MGIID: 1919140
• Length: 211
• Species: Mus musculus
• Alignment Length: 195
• Identity: 57/195 - (29%)
• Similarity: 98/195 - (50%)
• Gaps: 6/195 - (3%)

  Fly     4 EIKADIIVEAMEVLVNHILYVRGIYPSHIFKMKRMYNSPIYVSIFPPLNNYLAGVLKSAQELLRR 68
            ::.||::.|.:||.|:.|||||.:||..||:.::.||.|:.:|..|.||.|:...|...:.||.:
Mouse    13 QVVADVLSEFLEVAVHLILYVREVYPVGIFQKRKKYNVPVQMSCHPELNQYIQDTLHCVKPLLEK 77

  Fly    69 RELQCLELIVYQKENEKLESYKMQLETQRS--GLPAEDHLMEFEQNMRSVIYKISQRLNQAPKLP 131
            .:::.:.:::..||:..:|.:..:: ||..  .:.::..|...||.:|:.|.|||.........|
Mouse    78 NDVEKVVVVILDKEHRPVEKFVFEI-TQPPLLSINSDSLLSHVEQLLRAFILKISVCDAVLDHNP 141

  Fly   132 AGSCQFKVHLHTTQEAFIRFSHDSQYQEFPWLQTQKTESQATGRTVYLLPLARVDDLGLKMDVLI 196
            .| |.|.|.:||.:.|..........::|||:...  |.........|:||..:....|||.:.:
Mouse   142 PG-CTFTVLVHTREAATRNMEKIQVIKDFPWILAD--EQDVHMHDPRLIPLKTMTSDILKMQLYV 203

  Fly   197  196
            Mouse   204  203

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Rev7	NP_649555.1	None
Mad2l2	NP_001292349.1	HORMA	18..>103	CDD:396743	27/85 (32%)
		Mediates interaction with REV1 and REV3L and homodimerization. /evidence=ECO:0000250	21..155		44/135 (33%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C167835673
Domainoid	1	1.000	62	1.000	Domainoid score	I10351
eggNOG	1	0.900	-	-		E1_KOG3186
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	87	1.000	Inparanoid score	I5140
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG59766
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0006157
OrthoInspector	1	1.000	-	-		oto95175
orthoMCL	1	0.900	-	-		OOG6_104299
Panther	1	1.100	-	-	LDO	PTHR11842
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R1083
SonicParanoid	1	1.000	-	-		X5884
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
	14	13.790