DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG2926 and AT3G05670

DIOPT Version :9

Sequence 1:	NP_649554.1	Gene:	CG2926 / 40676	FlyBaseID:	FBgn0037344	Length:	2296	Species:	Drosophila melanogaster
Sequence 2:	NP_001325507.1	Gene:	AT3G05670 / 819734	AraportID:	AT3G05670	Length:	883	Species:	Arabidopsis thaliana

Alignment Length:	723	Identity:	154/723 - (21%)
Similarity:	249/723 - (34%)	Gaps:	171/723 - (23%)

- Green bases have known domain annotations that are detailed below.

  Fly     3 DRDSDAVSDAGPRLSQQ----------------RGQRNRRIIMRIEFKDSEDSASDQDRDDRPSC 51
            |.|.|..:|....|.::                :|.:.:|             .|.:.|..|..|
plant   228 DGDEDFTADEDVSLDEEEEEEIIACNKNALKVCKGNKRKR-------------RSGEGRKRRKKC 279

  Fly    52 SAA-TRLRRSTRR-----QEVASHSDSDSV-----PRKSTRKLRNRYGPR--------SDCSSSG 97
            |.| |||.|..:|     ::.....|.|.|     .||..:...:|..||        ||.:|||
plant   280 SVAKTRLTRGRKRRVRNTKKGVDEDDDDFVDDCLPARKKAKTKSSRPRPRRRCTVPSDSDVASSG 344

  Fly    98 -SDIDQLPTRTRKRKKVESSDEEEPERTPNAVGRIQPMPADPDDGFSSDISSNDL--LEKCP--- 156
             ||.:.            :..|||.|:...| |.:.....:..........:.||  |.|.|
plant   345 ESDYEY------------TISEEEREQIREA-GSLLKSSVNHASSIRQTTVNKDLPQLRKSPVKK 396

  Fly   157 ---------------ICLLTFRQQEI----GTPATCEHIFCAACIDAWSRNVQTCPIDRIEFDRI 202
                           :|.:...::::    ||...|.|.||..||..||:....||:.:..| |.
plant   397 GEKKVELVKRDVIKNVCGICLSEEDMRRLKGTLDCCSHYFCFTCIMEWSKVESRCPLCKQRF-RT 460

  Fly   203 IVRDSYASRRV-VREVRLDLSKSNTELVVDDEADTAALSEEEVTNCEICESPDREDVMLLCDSCN 266
            |.:.:.::..| :|||.:.:.:.:......:|...:.|...|...|..|...|.:.:|||||.|:
plant   461 ISKPARSTPGVDLREVVIPVPERDQVYQPTEEELRSYLDPYENIICTECHQGDDDGLMLLCDLCD 525

  Fly   267 QGYHMDCLDPPLYEIPAGSWYCDNCIDSDDEDDNEQLELADDLDQLY---EDIRGMGLPETRLRV 328
            ...|..|:... .|:|.|:|||:.|         ..:.|.....|.:   |..||.|.
plant   526 SSAHTYCVGLG-REVPEGNWYCEGC---------RPVALGSASSQTHIISEQQRGSGF------- 573

  Fly   329 REVQEPPRILRTRQNERIRAAVLRRTRSGATSAEDSTLTRTRTRTTTTTTTTTTTTRRTTTSTKK 393
              ...|..::.:.|.:.:...|..||    .......|...|........::.:....||.|
plant   574 --YSRPSPLVVSGQYQDVSLIVSPRT----PFFNGENLFSPRIPNGDAQGSSPSGLGATTLS--- 629

  Fly   394 RPVQRRRRRRTRYRTYVVEYD-LNNFDEKFALKTSKKVIRRRRRRRRRGVATASSEGPGRRLSAS 457
                 |||...|:...::..| |.|...:....:|.            |..| :..|.||.:..|
plant   630 -----RRRTLHRHIQNIINGDRLINMGARTGGTSSD------------GFVT-TQIGHGRTIDPS 676

  Fly   458 KRLAEQ-MGVKSEGFQSSHLSGGTASSFSLFGNANDLEYFSD-----SEPDAVSQIS-SAGLGST 515
            :.:|.| .|:.........|....    ||. :|:|.|..|.     ...:|..::| :..||..
plant   677 QPVASQETGISLYAISEERLPNNN----SLI-SAHDPELLSPKLDEFGSEEAFRRLSNNTFLGER 736

  Fly   516 AVQTSVRIG-SIGAPRIRKALLQGKARIAAPPTAPTSAPAADILSSILDLQDRWHDASRNLGEVH 579
            .:......| :.|.|     |:..:.|:.:......|:.|.:.|...:....:...:..:||:..
plant   737 PIDLGFHHGLAQGDP-----LVSNQQRLHSHMPNTMSSMAGERLQERVKAHLKNLSSQNDLGQTT 796

  Fly   580 IRADGTLNIPQRPAPTATEAPLPKAGTSKTEKHLTQAPLYQQGGGGPNYNRGGGAGSSDSYNNRY 644
            .....|.:|....|....|       ...:|.||...|:     ...:::...|:.||.|
plant   797 FDEISTCSIHTILAACGLE-------HESSEVHLVPPPV-----TCTHHHMTPGSSSSSS----- 844

  Fly   645 SGNTSYRG 652
            ||::..:|
plant   845 SGSSLMKG 852

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG2926	NP_649554.1	zf-RING_2	155..196	CDD:290367	14/62 (23%)
CG2926	NP_649554.1	PHD_PHRF1	246..291	CDD:277011	17/44 (39%)
AT3G05670	NP_001325507.1	RING-HC_Topors	413..455	CDD:319488	13/41 (32%)
AT3G05670	NP_001325507.1	PHD_SF	506..549	CDD:419867	17/43 (40%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_111428
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.810