Protein Alignment CG2926 and SCAF1

DIOPT Version :9

• Sequence 1: NP_649554.1
• Gene: CG2926 / 40676
• FlyBaseID: FBgn0037344
• Length: 2296
• Species: Drosophila melanogaster
• Sequence 2: XP_011525496.1
• Gene: SCAF1 / 58506
• HGNCID: 30403
• Length: 1315
• Species: Homo sapiens
• Alignment Length: 1710
• Identity: 357/1710 - (20%)
• Similarity: 542/1710 - (31%)
• Gaps: 679/1710 - (39%)

  Fly   791 PPASLPWNSP-LFKITPLQQAPAKSNDGNQNDDVD----------NC--PNFSIYSQESQAVANA 842
            ||...|..|| .|.:..:|||...|..|:..:|.|          .|  |.....||||.....|
Human    25 PPDRDPTLSPSAFILRAIQQAVGSSLQGDLPNDKDGSRCHGLRWRRCRSPRSEPRSQESGGTDTA 89

  Fly   843 SAM----------------------PSGVPHGPADASDKDDDDMNEDLVQLDDDDEDTDIPLPL- 884
            :.:                      ||.:...|.::     :||.|.:.::...|.| .||||:
Human    90 TVLDMATDSFLAGLVSVLDPPDTWVPSRLDLRPGES-----EDMLELVAEVRIGDRD-PIPLPVP 148

  Fly   885 -------------------------------------GPEPEPVPEKV-------PKSSDD---- 901
                                                 ||.|.|.|...       |.||..
Human   149 SLLPRLRAWRTGKTVSPQSNSSRPTCARHLTLGTGDGGPAPPPAPSSASSSPSPSPSSSSPSPPP 213

  Fly   902 ---------------DLYEPENPTEEPEEPEMFEESCDAVPTEKSESSDHEPSNSNVQAAA---- 947
                           |:|:|.:||:|...|.         |..:.:....||:.||..::|
Human   214 PPPPPAPPAPPAPRFDIYDPFHPTDEAYSPP---------PAPEQKYDPFEPTGSNPSSSAGTPS 269

  Fly   948 PEENDAEEARTRSTPSPLVKEDRAADRDRAKGVLE-----------LYDDSDWEELDIDKPKEFE 1001
            |||.:.||..         :|:...|.:..:|:.:           :|||:   .|..|.|.:..
Human   270 PEEEEEEEEE---------EEEEEEDEEEEEGLSQSISRISETLAGIYDDN---SLSQDFPGDES 322

  Fly  1002 KALLTETEAQ-VSPKRAPSKRP---PSKKDTSLERDVNESGSEHEQDR--------------SYT 1048
                ...:|| ..|..||...|   .::.|.::.|.|...|:|.|..|              :..
Human   323 ----PRPDAQPTQPTPAPGTPPQVDSTRADGAMRRRVFVVGTEAEACREGKVSVEVVTAGGAALP 383

  Fly  1049 PCL--------DEKNLAEEEE-----AGTTHQNNVSTSPKTRSSKVSGDEDEPEKAVGTDIQSED 1100
            |.|        :|..:.:.||     .........:..|...:|.....:..|:.......:.:|
Human   384 PPLLPPGDSEIEEGEIVQPEEEPRLALSLFRPGGRAARPTPAASATPTAQPLPQPPAPRAPEGDD 448

  Fly  1101 ELNNENESPRRSRSRGTANNKKDKSKSRSKRNKGETFKKVGKRQKDRNYRGDKSEPDRSPRPDSR 1165
            .|:...||......:...........:...|..|...::....|:...||.....|..:|.| :.
Human   449 FLSLHAESDGEGALQVDLGEPAPAPPAADSRWGGLDLRRKILTQRRERYRQRSPSPAPAPAP-AA 512

  Fly  1166 SLTPKMRSKSPRVSKSISRSRSGSRSRCKSKSFSRSRS----RSPSRSRNRRRRNSRSKSYSRSH 1226
            :..|..|.||.|     .|.|||......|.|.....:    .||..|:..|.|:.:..|::.|.
Human   513 AAGPPTRKKSRR-----ERKRSGEAKEAASSSSGTQPAPPAPASPWDSKKHRSRDRKPGSHASSS 572

  Fly  1227 SRSRSRSNSHSRQRFSFRGRDHQRGFFRGRGGLRLNYRNQQFHNRPFQHYGQNYHQNQNYHHQHN 1291
            :|.||||.|.||..     |...|...|.|||.|                     ::::...:..
Human   573 ARRRSRSRSRSRST-----RRRSRSTDRRRGGSR---------------------RSRSREKRRR 611

  Fly  1292 QHQNYFPPNQHGQHQQYFQRPKRRELPRYDVRNVVGTSRHQTQAKDRY-GRDAMRSHRSRSGRRN 1355
            :.::..||                          ..||...:..::|: |:     ||...|.:.
Human   612 RRRSASPP--------------------------PATSSSSSSRRERHRGK-----HRDGGGSKK 645

  Fly  1356 SRSFSRSVSRDSRVSLRSRSGSPKRRSFSMSPTPPP--------------GTSPP------PHKH 1400
            .:..||     ||...||..||.|    :.:|.|||              |..||      .|..
Human   646 KKKRSR-----SRGEKRSGDGSEK----APAPAPPPSGSTSCGDRDSRRRGAVPPSIQDLTDHDL 701

  Fly  1401 GRGRQTST----NRRYARSPSPAPSPRNERATSPVQSVHSRRSRSHTPNRINGD--GNRSSLYMG 1459
            ...::|.|    ::...|.|||||      |:||      :|...:....::|:  |.:||
Human   702 FAIKRTITVGRLDKSDPRGPSPAP------ASSP------KREVLYDSEGLSGEERGGKSS---- 750

  Fly  1460 SPHYTPRISRSRSRSRSKSPKDMHKKKKKKSDKKKRRKRTGSSSPTTAARMRRISRQRDPFEDAD 1524
                                             :|.|:|:|::|.::::|
Human   751 ---------------------------------QKDRRRSGAASSSSSSR--------------- 767

  Fly  1525 DFLAPQRKRKKAGITTGQWSPSPSPGRCDFLHDSALQDKNSSWTPPLGTPKGGHYNNDGGLTPKK 1589
                .:..|:||                                            .|||...:.
Human   768 ----EKGSRRKA--------------------------------------------LDGGDRDRD 784

  Fly  1590 TKRKRDKSKKKRKQHQLEKPRKEKKRKRRTQTPEPLPSKEVFASGNNILVSVSFNKESNTNNASA 1654
            ..|.||:.:..:|    .:|.||   ...:..|.|.|.   .:||            |.::::|:
Human   785 RDRDRDRDRSSKK----ARPPKE---SAPSSGPPPKPP---VSSG------------SGSSSSSS 827

  Fly  1655 TLSSQQ---QSVVTIPPGREDLLSNRMTSMTSMASMASNSNICSAVGAV-KKTKRKRKKLEAKPV 1715
            :.||::   ||.|.:      |:...::|.|.....||     :.:|:: .|..|.|:
Human   828 SCSSRKVKLQSKVAV------LIREGVSSTTPAKDAAS-----AGLGSIGVKFSRDRE------- 874

  Fly  1716 AIIDLERSPFQVHQEPADVIVLTDSEDATEPLSSRRERERDRDHELMRENGQREKTPQVGSLDAI 1780
                 .||||....|.|...:...:..:|:|                      :||.......|
Human   875 -----SRSPFLKPDERAPTEMAKAAPGSTKP----------------------KKTKVKAKAGA- 911

  Fly  1781 METSYENMTQSTGPKTPPEPPLVKFNLPTKKIQHKVRNN----------PLHEDVDDINSADELE 1835
                  ..|:.|..||.|           .|.:.|||:.          .|.:...|
Human   912 ------KKTKGTKGKTKP-----------SKTRKKVRSGGGSGGSGGQVSLKKSKAD-------- 951

  Fly  1836 ASCSMAP----AEQTPQHGHASHDGGQKIGPNTPPESGPCSPDAYDPFEPTKSPSLSPRSPTLTP 1896
             |||.|.    ||:|...|   .:...|: |:|||                  |..:|..|.|||
Human   952 -SCSQAAGTKGAEETSWSG---EERAAKV-PSTPP------------------PKAAPPPPALTP 993

  Fly  1897 -SQNLDQQTVSMPASGAIGPGSGDKGESDGAHVTGSNASTNTQAQGNALNPVDLVMALMNKPNQS 1960
             ||.:|....:...|......:.:.|...||...........:.
Human   994 DSQTVDSSCKTPEVSFLPEEATEEAGVRGGAEEEEEEEEEEEEE--------------------- 1037

  Fly  1961 GSIQQESEVSSAQYISSSSLSLSLGVGSSTGGGGGGAGGGD------------------NHDKTA 2007
               ::|.|...|...::|:.:.:.....|.|...|.:|..|                  |.....
Human  1038 ---EEEEEQQPATTTATSTAAAAPSTAPSAGSTAGDSGAEDGPASRVSQLPTLPPPMPWNLPAGV 1099

  Fly  2008 DGKTITVLSNVLL-------------TSSSVVSSSQHIPSISSPTPPSKKLTPLPKAGGSVASSS 2059
            |..|..||:...|             .:..::.::..|.|...| |.|..:||.|
Human  1100 DCTTSGVLALTALLFKMEEANLASRAKAQELIQATNQILSHRKP-PSSLGMTPAP---------- 1153

  Fly  2060 SGVGNIPTTSSGIGGTRNGSGLGNAGGSSNALDDSFSMEIESPYSPGSADYEDLFEPPIPLEASR 2124
                 :||:            ||...|.|:.|            .|||          :||
Human  1154 -----VPTS------------LGLPPGPSSYL------------LPGS----------LPL---- 1175

  Fly  2125 RAKGGATGGKVEIFDNLFGSSSPISNIRMTSRYNTAVGKKSNRTKADRKSKVKGARNPDFYDDVP 2189
               ||.            ||:.|           |..|..:...|.:..|..:|..:.|.|
Human  1176 ---GGC------------GSTPP-----------TPTGLAATSDKREGSSSSEGRGDTDKY---- 1210

  Fly  2190 NSATDLQNKDRLLRKLNRQERVVEEVKLVLKPYFNKKAITKDDYKDIMRRAVPKICHSRSGEINP 2254
                        |:||:.|||.||||||.:|||:.||.|||::||||:|:||.|||||:||||||
Human  1211 ------------LKKLHTQERAVEEVKLAIKPYYQKKDITKEEYKDILRKAVHKICHSKSGEINP 1263

  Fly  2255 HKIKNLIDAYVRKFR--AKH 2272
            .|:.||:.|||:::|  .||
Human  1264 VKVSNLVRAYVQRYRYFRKH 1283

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG2926	NP_649554.1	zf-RING_2	155..196	CDD:290367
		PHD_PHRF1	246..291	CDD:277011
SCAF1	XP_011525496.1	None

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C165159455
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG0825
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	1	0.950	-	0	Normalized mean entropy	S8166
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	1	0.960	-	-
User_Submission	0	0.000	Not matched by this tool.
	5	4.740