DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG2926 and SPCC126.07c

DIOPT Version :9

Sequence 1:	NP_649554.1	Gene:	CG2926 / 40676	FlyBaseID:	FBgn0037344	Length:	2296	Species:	Drosophila melanogaster
Sequence 2:	NP_588450.1	Gene:	SPCC126.07c / 2539058	PomBaseID:	SPCC126.07c	Length:	571	Species:	Schizosaccharomyces pombe

Alignment Length:	493	Identity:	106/493 - (21%)
Similarity:	176/493 - (35%)	Gaps:	159/493 - (32%)

- Green bases have known domain annotations that are detailed below.

  Fly   133 PMPADPDDGFSSDISSNDLLEKCPICLLTF------RQQEIGTPAT--------------CEHIF 177
            |.|||.|..           |:|.|||...      :......||:              |.|.|
pombe     7 PKPADSDSS-----------EECIICLSNLPNCPLDQWDSSSVPASISSTLDGLRIAKIPCGHYF 60

  Fly   178 CAACIDAWSRNVQTCPIDRIEFDRIIVRDS-----YASRRVVREVRLDLSKSNTELVVDDEADTA 237
            ...|:::|.|...|||:.|.||.::.|.:.     |.:..|..:.:   |.:|.....:||.
pombe    61 HNHCLESWCRVANTCPLCRTEFLKVDVLEFVKGPWYRAYPVEEKTQ---SVANAGEPFEDEG--- 119

  Fly   238 ALSEEEVTNCEICESPDREDVMLLCDSCNQGYHMDCLDPPLYEIPAGSWYCDNCIDSDDEDDNEQ 302
                .|...|.||...|..:|:||||.|:..||..||:  :..:|...:||.||:..:.: :||.
pombe   120 ----SETCRCVICGRSDHAEVLLLCDGCDDAYHTYCLN--MDAVPIEEFYCPNCVLLNYQ-ENET 177

  Fly   303 LELADDL----------------------------------------DQLYEDIRGMGLPETRLR 327
            |.....|                                        |.|..|:...|:.:.||.
pombe   178 LSSRISLSRRGQTRRRRVGAAARASRVSQQQQRAWTRAWNAIRNRAWDALNSDLSYYGMQQERLP 242

  Fly   328 VREVQEPPRILRTR-QNERIRAAVL-------RRTRSGATSAE--------DSTLTRTRTRTTTT 376
            .|:|..  .:||.| ::.|:|:..|       |..::..|:|.        |..|....:..:..
pombe   243 ARDVSS--ELLRRRIESARLRSNQLNEPVEQPRVVQTPVTNASEQQAWNDFDEILHANSSVHSVA 305

  Fly   377 TTTTTTTTRRTTTSTKKRPVQRRRRRRTRYRTYVVEYDLNNFDEKFALKTSKKVIRRRRRRRRRG 441
            |..|.:..|.::...::.|::...::.||   :|.:.:..:.|            ||::|..||.
pombe   306 TEATISNPRPSSGRFQQTPIEEHHQQDTR---FVNDPNSTSHD------------RRQKRPTRRH 355

  Fly   442 VATASSEGPGRRLSASKRLAEQMGVKSEGFQSSHLSGGTASS-------FSLFGNAN-------D 492
            :..::                    ||.|  ||.:.|..:||       .||..|.|       |
pombe   356 IPCSN--------------------KSSG--SSTVLGNNSSSKSENSFLASLISNINQPSTSRID 398

  Fly   493 LEYFSDSEPDAVSQISSAGLGSTAVQTSVRIGSIGAPR 530
            ..:....:.:..:..|.|..|::.|..:....:: :||
pombe   399 TSFMLSLQHEIKNSHSEASDGTSDVHLTPLFSNL-SPR 435

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG2926	NP_649554.1	zf-RING_2	155..196	CDD:290367	15/60 (25%)
CG2926	NP_649554.1	PHD_PHRF1	246..291	CDD:277011	17/44 (39%)
SPCC126.07c	NP_588450.1	zf-RING_2	16..79	CDD:290367	16/62 (26%)
SPCC126.07c	NP_588450.1	PHD_PHRF1	124..167	CDD:277011	17/44 (39%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG0825
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0007147
OrthoInspector	1	1.000	-	-		oto101253
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	LDO	PTHR12618
Phylome	0	0.000	Not matched by this tool.
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R2007
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	5	5.030