DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CRMP and ALN

DIOPT Version :9

Sequence 1:	NP_730954.2	Gene:	CRMP / 40675	FlyBaseID:	FBgn0023023	Length:	594	Species:	Drosophila melanogaster
Sequence 2:	NP_567276.1	Gene:	ALN / 825836	AraportID:	AT4G04955	Length:	506	Species:	Arabidopsis thaliana

Alignment Length:	516	Identity:	127/516 - (24%)
Similarity:	205/516 - (39%)	Gaps:	124/516 - (24%)

- Green bases have known domain annotations that are detailed below.

  Fly    14 HLQSAQNRVYIKNGEIVNHDKSFKADVYIEDGIIKFVGPSSEI----TIPGGVRTIDASGLMIIP 74
            |...:..|:...||.|       ...|.::.|||  |....|:    :....|:.||....:::|
plant    44 HYWISSKRIVTPNGLI-------SGSVEVKGGII--VSVVKEVDWHKSQRSRVKVIDYGEAVLMP 99

  Fly    75 GGIDPHTHMQLPFGGAVAVDDFYHGTKAAVAGGTTMIIDF--------VLPNKHESMIEAYDKWR 131
            |.||.|.|:..|  |....:.|..|||||.|||.|.::|.        |.|...:..|||
plant   100 GLIDVHVHLDDP--GRSEWEGFPSGTKAAAAGGITTLVDMPLNSFPSTVSPETLKLKIEA----- 157

  Fly   132 SWADPKVCCDYGLHVGITWW---------SKSVSEEIGILCKELGVNSFKTFMAYKGLYQLNDSD 187
                    ....:||.:.:|         :.|..|.:    .:.||...|:||...|   :||..
plant   158 --------AKNRIHVDVGFWGGLVPDNALNSSALESL----LDAGVLGLKSFMCPSG---INDFP 207

  Fly   188 LLDVFERIRHLNGVA------MVHAENGDIIAKNTQRLLAEGI-NGPEGHEL---SRPEEVEAEA 242
            :.::......|:.:|      :||||    |.::.:  :.:|. |.|..:..   :||...|..|
plant   208 MTNITHIKEGLSVLAKYKRPLLVHAE----IERDLE--IEDGSENDPRSYLTYLKTRPTSWEEGA 266

  Fly   243 VHRACVL------------AHQADCPLYVVHVMSKSAGIELARARHRYRGRYIMGETLAAALGTD 295
            :.....:            ||     |::||:...|:.::|.:   ..:|:   |:::     |.
plant   267 IRNLLSVTENTRIGGSAEGAH-----LHIVHLSDASSSLDLIK---EAKGK---GDSV-----TV 315

  Fly   296 ATCCQHLGFDAE------AAHVLSPPLRPDKTTPEFLMKLLANDDLQLTGSDNCTFNKEHKALGK 354
            .||..:|.|.||      .....|||:| |....|.|.:.|...|:.:..||:.....|.|.:..
plant   316 ETCPHYLAFSAEEIPEGDTRFKCSPPIR-DAANREKLWEALMEGDIDMLSSDHSPTKPELKLMSD 379

  Fly   355 GDFTKIPNGVNGVEDRMSLVWEKGVHAGLLDPCRFVAVT---STNAAKIFNIYPQKGRIAVGSDA 416
            |:|.|...|::.::..:.:.|..|...|:    ....||   |...:|:..:: .||.:.||..|
plant   380 GNFLKAWGGISSLQFVLPITWSYGKKYGV----TLEQVTSWWSDRPSKLAGLH-SKGAVTVGKHA 439

  Fly   417 DIVIWNPNATRTISKD--THHHACDFNIFEGMTVHG--VCEFVLVRGRICAERGNVRVAEG 473
            |:|:|.|.|...:.:|  .|......:.:.|..:.|  |..||         |||:...||
plant   440 DLVVWEPEAEFDVDEDHPIHFKHPSISAYLGRRLSGKVVSTFV---------RGNLVFGEG 491

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CRMP	NP_730954.2	D-HYD	22..475	CDD:238639	125/508 (25%)
CRMP	NP_730954.2	PRK09060	24..483	CDD:181632	125/506 (25%)
ALN	NP_567276.1	PLN02795	1..505	CDD:178392	127/516 (25%)
ALN	NP_567276.1	L-HYD_ALN	44..503	CDD:238640	127/516 (25%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0044
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D719800at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	2.820