Protein Alignment CRMP and dhp-2

DIOPT Version :9

• Sequence 1: NP_730954.2
• Gene: CRMP / 40675
• FlyBaseID: FBgn0023023
• Length: 594
• Species: Drosophila melanogaster
• Sequence 2: NP_501797.1
• Gene: dhp-2 / 177852
• WormBaseID: WBGene00000964
• Length: 520
• Species: Caenorhabditis elegans
• Alignment Length: 569
• Identity: 292/569 - (51%)
• Similarity: 364/569 - (63%)
• Gaps: 57/569 - (10%)

  Fly    24 IKNGEIVNHDKSFKADVYIEDGIIKFVGPSSEITIPGGVRTIDASGLMIIPGGIDPHTHMQLPFG 88
            ||||.|||.|..||:||.:.||.|..:.||.:.|  .|:..:||:..::|||||||||||||||.
 Worm     5 IKNGTIVNDDAIFKSDVLVLDGRIVEIAPSIQPT--PGLEVVDATDRLVIPGGIDPHTHMQLPFM 67

  Fly    89 GAVAVDDFYHGTKAAVAGGTTMIIDFVLPNKHESMIEAYDKWRSWADPKVCCDYGLHVGITWWSK 153
            |.:|.|||:.||:||||||||||||||:|.|.||::.|||:||.||||||.|||||.:.||.|..
 Worm    68 GEIAKDDFHRGTEAAVAGGTTMIIDFVIPTKGESLLVAYDRWRGWADPKVVCDYGLSMAITSWGP 132

  Fly   154 SVSEEIGILC-KELGVNSFKTFMAYKGLYQLNDSDLLDVFERIRHLNGVAMVHAENGDIIAKNTQ 217
            .:::|:.|:. .|.|:||||.|:||.|::.:.|.:......:...|..:|.||||||.:||:..:
 Worm   133 EIAKEMEIVTGAEYGINSFKFFLAYAGVFMVRDEEFYQGMIQCAKLRALARVHAENGSVIAERCE 197

  Fly   218 RLLAEGINGPEGHELSRPEEVEAEAVHRACVLAHQADCPLYVVHVMSKSAGIELARARHRYRGRY 282
            .||:.||.|||||..|||||:||||..|||.:|.||:|||||||||||  |...|.|.||.:|..
 Worm   198 HLLSSGITGPEGHTQSRPEELEAEATFRACTMASQANCPLYVVHVMSK--GAAAAIAHHRKKGAV 260

  Fly   283 IMGETLAAALGTDATCCQHLGFDAEAAHVLSPPLRPDKTTPEFLMKLLANDDLQLTGSDNCTFNK 347
            :.||.:||.|.||.:...:..:...|.:|:||||..|.:||..||||||..:|.||.:|||||:.
 Worm   261 VFGEPIAAGLATDGSHYYNEDWLHAARYVMSPPLSRDPSTPSALMKLLAAGELHLTATDNCTFDC 325

  Fly   348 EHKALGKGDFTKIPNGVNGVEDRMSLVWEKGVHAGLLDPCRFVAVTSTNAAKIFNIYPQKGRIAV 412
            :.|:|||.|||||||||||||||||:||:||||||::||.||||||||.||||||.|||||||||
 Worm   326 QQKSLGKDDFTKIPNGVNGVEDRMSVVWDKGVHAGIIDPMRFVAVTSTMAAKIFNCYPQKGRIAV 390

  Fly   413 GSDADIVIWNPNATRTISKDTHHHACDFNIFEGMTVHGVCEFVLVRGRICAERGNVRVAEGFGRF 477
            ||||||||||.||||||||||||||.||||||||.||||.|..:.|||.....|.::..:|.|:|
 Worm   391 GSDADIVIWNANATRTISKDTHHHAIDFNIFEGMQVHGVPEITISRGRTVWANGQLKTVQGSGQF 455

  Fly   478 IPTPVRPPFVYDIIEGKVQSQPEEQHEEKQNGSMAKRFAELDIQIPVQEPISAMLAGNLAMPAEG 542
            ||.......|:..::.:.::                           .||:...     .:|.|.
 Worm   456 IPLAPDSQIVFSAVDNRKKA---------------------------MEPVKID-----RIPYEP 488

  Fly   543 SLCSTPSVRGRVDGKRDLQESSFSISEELDRSGVRACIKVKNPPGGKSS 591
            |...||.....:                :.::.|||.|    ||||.||
 Worm   489 SALQTPDANANI----------------VVKAPVRAAI----PPGGASS 517

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CRMP	NP_730954.2	D-HYD	22..475	CDD:238639	270/451 (60%)
		PRK09060	24..483	CDD:181632	274/459 (60%)
dhp-2	NP_501797.1	D-HYD	3..453	CDD:238639	270/451 (60%)
		PRK09060	3..446	CDD:181632	269/444 (61%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C160157446
Domainoid	1	1.000	503	1.000	Domainoid score	I172
eggNOG	1	0.900	-	-		E1_COG0044
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H20359
Inparanoid	1	1.050	553	1.000	Inparanoid score	I611
Isobase	1	0.950	-	0.917438	Normalized mean entropy	S1869
OMA	1	1.010	-	-		QHG54576
OrthoDB	1	1.010	-	-		D174151at33208
OrthoFinder	1	1.000	-	-		FOG0000315
OrthoInspector	1	1.000	-	-		otm14670
orthoMCL	1	0.900	-	-		OOG6_100676
Panther	1	1.100	-	-	LDO	PTHR11647
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R5547
SonicParanoid	1	1.000	-	-		X218
SwiftOrtho	1	1.000	-	-
TreeFam	1	0.960	-	-
	18	17.750