Protein Alignment CRMP and Crmp1

DIOPT Version :10

• Sequence 1: NP_730954.2
• Gene: CRMP / 40675
• FlyBaseID: FBgn0023023
• Length: 594
• Species: Drosophila melanogaster
• Sequence 2: NP_001129530.1
• Gene: Crmp1 / 12933
• MGIID: 107793
• Length: 686
• Species: Mus musculus
• Alignment Length: 595
• Identity: 279/595 - (46%)
• Similarity: 395/595 - (66%)
• Gaps: 35/595 - (5%)

  Fly     5 PKPVKKVPIHLQSAQ-NRVYIKNGEIVNHDKSFKADVYIEDGIIKFVGPSSEITIPGGVRTIDAS 68
            |.| :.:|:...:.| :|:.|:.|.|:|.|:||.||||:|||:||.:|  ..:.:||||:||:|:
Mouse   114 PAP-RDLPLGRDNGQSDRLLIRGGRIINDDQSFYADVYLEDGLIKQIG--ENLIVPGGVKTIEAN 175

  Fly    69 GLMIIPGGIDPHTHMQLPFGGAVAVDDFYHGTKAAVAGGTTMIIDFVLPNKHESMIEAYDKWRSW 133
            |.|:||||||.:|::|.|..|..:.|||:.|||||:|||||||||.|:|....|::.:::||...
Mouse   176 GRMVIPGGIDVNTYLQKPSQGMTSADDFFQGTKAALAGGTTMIIDHVVPEPGSSLLTSFEKWHEA 240

  Fly   134 ADPKVCCDYGLHVGITWWSKSVSEEIGILCKELGVNSFKTFMAYKGLYQLNDSDLLDVFERIRHL 198
            ||.|.||||.|||.||.|...|.||:.:|.::.|||||:.:||||.|||::||.|.:.|..::.|
Mouse   241 ADTKSCCDYSLHVDITSWYDGVREELEVLVQDKGVNSFQVYMAYKDLYQMSDSQLYEAFTFLKGL 305

  Fly   199 NGVAMVHAENGDIIAKNTQRLLAEGINGPEGHELSRPEEVEAEAVHRACVLAHQADCPLYVVHVM 263
            ..|.:|||||||:||:..:|:|..||.|||||.||||||:|||||.||..:|.:.:||:|:..||
Mouse   306 GAVILVHAENGDLIAQEQKRILEMGITGPEGHALSRPEELEAEAVFRAIAIAGRINCPVYITKVM 370

  Fly   264 SKSAGIELARARHRYRGRYIMGETLAAALGTDATCCQHLGFDAEAAHVLSPPLRPDKTTPEFLMK 328
            ||||...:|.||.  :|..:.||.:||:||||.|......:...||.|.||||.||.|||::|..
Mouse   371 SKSAADIIALARK--KGPLVFGEPIAASLGTDGTHYWSKNWAKAAAFVTSPPLSPDPTTPDYLTS 433

  Fly   329 LLANDDLQLTGSDNCTFNKEHKALGKGDFTKIPNGVNGVEDRMSLVWEKGVHAGLLDPCRFVAVT 393
            |||..|||:|||.:|.::...||:||.:||.||.||||:|:||::||:|.|..|.:|..:|||||
Mouse   434 LLACGDLQVTGSGHCPYSTAQKAVGKDNFTLIPEGVNGIEERMTVVWDKAVATGKMDENQFVAVT 498

  Fly   394 STNAAKIFNIYPQKGRIAVGSDADIVIWNPNATRTISKDTHHHACDFNIFEGMTVHGVCEFVLVR 458
            |||||||||:||:|||||||||||:|||:|:..:||:..:|....::||||||..||....|:.:
Mouse   499 STNAAKIFNLYPRKGRIAVGSDADVVIWDPDKMKTITAKSHKSTVEYNIFEGMECHGSPLVVISQ 563

  Fly   459 GRICAERGNVRVAEGFGRFIPTPVRPPFVYDIIEGKVQSQPEEQHEEKQNGSMAKRFAELDI-QI 522
            |:|..|.||:.|::|.|||||....|..:|..:  :::|:....|      |:::...:..: ::
Mouse   564 GKIVFEDGNISVSKGMGRFIPRKPFPEHLYQRV--RIRSKVFGLH------SVSRGMYDGPVYEV 620

  Fly   523 PVQEPISAMLAGNLAMPAEGSLCSTPSVRGRVDGKRDLQESSFSIS-EELD-----RSGVRACIK 581
            |.....:|        ||. |..|:|| :.:....|:|.:|:||:| .::|     |:|.|
Mouse   621 PATPKHAA--------PAP-SAKSSPS-KHQPPPIRNLHQSNFSLSGAQIDDNNPRRTGHR---- 671

  Fly   582 VKNPPGGKSS 591
            :..||||:|:
Mouse   672 IVAPPGGRSN 681

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CRMP	NP_730954.2	D-HYD	22..475	CDD:238639	241/452 (53%)
Crmp1	NP_001129530.1	D-HYD	131..580	CDD:238639	241/452 (53%)