DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CRMP and XB5950266

DIOPT Version :9

Sequence 1:	NP_730954.2	Gene:	CRMP / 40675	FlyBaseID:	FBgn0023023	Length:	594	Species:	Drosophila melanogaster
Sequence 2:	XP_031758421.1	Gene:	XB5950266 / 100498039	XenbaseID:	XB-GENE-5950267	Length:	496	Species:	Xenopus tropicalis

Alignment Length:	509	Identity:	135/509 - (26%)
Similarity:	208/509 - (40%)	Gaps:	89/509 - (17%)

- Green bases have known domain annotations that are detailed below.

  Fly    24 IKNGEIVNHDKSFKADVYIEDGIIKFVGPSSEITIPGGVRTIDASGLMIIPGGIDPHTHMQLPFG 88
            :::..:|..:....||:.|:||.|..:.|..:.:|..|.:.:||..|:::||.||||.|:..|
Frog    42 VRSRRVVTGNTISPADIIIKDGKIVGIQPWGKQSITVGSQLLDAGDLVVMPGIIDPHVHVNEP-- 104

  Fly    89 GAVAVDDFYHGTKAAVAGGTTMIIDFVLPNKHESMIEAYDKWRSWADPKVCCDYGLHVGITWWSK 153
            |....:.:...|:||.|||.|.|:|..|.:...:...:....:..|....|     .|.:.:|..
Frog   105 GRTDWEGYSTATRAAAAGGITTIVDMPLNSLPPTTSVSNFLTKLKAAEGQC-----FVDVAFWGG 164

  Fly   154 SVS----EEIGILCKELGVNSFKTFMAYKGLYQLNDSDLLDVFERIRHL---NGVAMVHAE---- 207
            .:.    |.:.:|  ..||..||.|:...|:.:.....|:|:...:..|   |.|.:.|||
Frog   165 VIPGNQLELVPML--HAGVAGFKCFLISSGVPEFPHVSLMDLHSAMSELQGTNSVLLFHAEFDDP 227

  Fly   208 -----NGDIIAKNTQRLLAEGINGPEGHELSRPEEVEAEAVHRACVLAHQADCPLYVVHVMS--- 264
                 |||.:...|  .||           |||..:|..||.....|..|.....::||:.|
Frog   228 SRAPTNGDPMQYET--FLA-----------SRPPHMEVAAVEAVANLCLQYKVRCHIVHLSSAMA 279

  Fly   265 -------KSAGIEL-ARARHRYRGRYIMGETLAA-ALGTDAT---CCQHLGFDAEAAHVLSPPLR 317
                   |.||..| ....|.|.       ||:| .:...||   ||              ||:|
Frog   280 LPIIRKAKKAGAPLTVETTHHYL-------TLSAEKIPPGATYFKCC--------------PPVR 323

  Fly   318 PDKTTPEFLMKLLANDDLQLTGSDNCTFNKEHKALGKGDFTKIPNGVNGVEDRMSLVWEKGVHAG 382
             :.:..|.|...|....:.:..||:.....:.|.|..|||.|...|:..::..:||.|......|
Frog   324 -EHSNKEALWNALLQGHIDMVVSDHSPCTPDLKLLQDGDFLKAWGGICSLQLGLSLFWSSARSRG 387

  Fly   383 --LLDPCRFVAVTSTNAAKIFNIYPQKGRIAVGSDADIVIWNPNATRTISKDTHHHACDFNIFEG 445
              |||..|.:   |:|.||:.::..:||.|..|.|||:|||:|:....:.:.:.||......:.|
Frog   388 FSLLDIPRLL---SSNPAKLSSLDGRKGAIKPGYDADLVIWDPDKEYQVHEASLHHKNKLTPYLG 449

  Fly   446 MTVHGVCEFVLVRGRICAERGNVRVAEGFGRFIPTPVRPPFVYDIIEGKVQSQP 499
            ..:.|..|..:|.|.:...:         ||..|.|...|.:...:|....|.|
Frog   450 FQLCGETEATIVGGILVYYK---------GRHCPVPAGKPLLIQTMELPEPSDP 494

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CRMP	NP_730954.2	D-HYD	22..475	CDD:238639	127/483 (26%)
CRMP	NP_730954.2	PRK09060	24..483	CDD:181632	131/491 (27%)
XB5950266	XP_031758421.1	metallo-dependent_hydrolases	41..482	CDD:412281	132/495 (27%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D719800at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	1.010