DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG2931 and rbm42

DIOPT Version :9

Sequence 1:	NP_649552.1	Gene:	CG2931 / 40673	FlyBaseID:	FBgn0037342	Length:	302	Species:	Drosophila melanogaster
Sequence 2:	XP_012821912.1	Gene:	rbm42 / 493283	XenbaseID:	XB-GENE-5896695	Length:	393	Species:	Xenopus tropicalis

Alignment Length:	402	Identity:	135/402 - (33%)
Similarity:	191/402 - (47%)	Gaps:	131/402 - (32%)

- Green bases have known domain annotations that are detailed below.

  Fly     4 KRRNIEDELSRFEAE-----ISKPPARNLFVP----NQVRPIIAANTYQNSQHKLQHHQGNGGS- 58
            |.:.:|.|::.||.|     ::.||...:.:|    ..:|.|||.|||...|..|:.......|
Frog     9 KMKAMEAEMALFEQEVLGAPVALPPVDPVPLPIPAVPVIRAIIATNTYSQVQQSLEARAAAAASV 73

  Fly    59 --RLTVPP-------------------------------------------------------PP 66
              .:.|||                                                       |.
Frog    74 VGPMIVPPVPFVGPAAIPPPRPPVMRPSFIPHALQRPAEPHGAMPRPSFIPHVLQQRAVGPRHPG 138

  Fly    67 MPPPPTFMSTFV--------------PTGSGGGSSKAMSATPV---------VLSSAPKLYQCRQ 108
            ||||...|:..:              |.|...|...|    ||         |:.||||:.
Frog   139 MPPPQPLMAHHMHGPPPPLMRHIPPPPLGMRAGPPPA----PVGPLPPPPRPVVPSAPKMN---- 195

  Fly   109 SVHVPTV-AAAPSI----DINAVSFDVTQ------KLKKLKAEKS--GPN-----PIAEEAIKAA 155
                ||| .|||::    .:.....::.:      :.:.|..|::  ||:     |:..|.:
Frog   196 ----PTVIQAAPTVYTAPPVRKPEEEIVEPPILPDEKETLSFEEAVIGPSMPEMEPVQPEVV--- 253

  Fly   156 RASSALQSFQTTERKKKDRK---TVRIAGGTVWEDTSLADWPDDDFRIFCGDLGNDVNDEVLTRT 217
                 |:..|..::|.|..|   .:|.|.||.|||.||.:|..||||||||||||:|||::|.|.
Frog   254 -----LEPVQEDKKKTKPEKLKRCIRTAAGTSWEDQSLLEWESDDFRIFCGDLGNEVNDDILARA 313

  Fly   218 FNKFPSFQRARVVRDKRTGKSKGFGFVSFREPADFIRAMKEMDGRYVGSRPIKLRKSTWRQRSLD 282
            |:::|||.||:|:|||||||:||:|||||::|.|::|||:||:|:||||||||||||.|:.|::|
Frog   314 FSRYPSFLRAKVIRDKRTGKTKGYGFVSFKDPNDYVRAMREMNGKYVGSRPIKLRKSQWKDRNMD 378

  Fly   283 VVKKKEREKQVL 294
            ||:||:|||:.|
Frog   379 VVRKKQREKKKL 390

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG2931	NP_649552.1	RRM_RBM42	192..274	CDD:240829	57/81 (70%)
CG2931	NP_649552.1	RRM	<194..>280	CDD:223796	59/85 (69%)
rbm42	XP_012821912.1	RRM_RBM42	288..370	CDD:240829	57/81 (70%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	120	1.000	Domainoid score	I5697
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	199	1.000	Inparanoid score	I3677
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0005503
OrthoInspector	1	1.000	-	-		oto104180
Panther	1	1.100	-	-	LDO	PTHR24012
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R1762
SonicParanoid	1	1.000	-	-		X3922
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	9	9.090