Protein Alignment CG12746 and PLPP2

DIOPT Version :10

• Sequence 1: NP_649551.4
• Gene: CG12746 / 40672
• FlyBaseID: FBgn0037341
• Length: 363
• Species: Drosophila melanogaster
• Sequence 2: NP_808211.1
• Gene: PLPP2 / 8612
• HGNCID: 9230
• Length: 309
• Species: Homo sapiens
• Alignment Length: 218
• Identity: 68/218 - (31%)
• Similarity: 95/218 - (43%)
• Gaps: 47/218 - (21%)

  Fly   109 PRRPDIVRGGELLFWVIVAPFLVTI----AFYWYT---RDRRDFR---AASW----AWTLALCMN 159
            |.|||.:..| |:..|.:...::.:    |:..||   ..|.||.   ||.:    .:.....::
Human    67 PYRPDTITHG-LMAGVTITATVILVSAGEAYLVYTDRLYSRSDFNNYVAAVYKVLGTFLFGAAVS 130

  Fly   160 GIPTSVLKITVGRPRPDYFYRCFPDGVMVLNTTSNGVDTSI---LDFNCTGLPGDINEGRKSFPS 221
            ...|.:.|..:||.||::...|.||.        :.|:.|:   |:..|.|.|.|:.|.|.||.|
Human   131 QSLTDLAKYMIGRLRPNFLAVCDPDW--------SRVNCSVYVQLEKVCRGNPADVTEARLSFYS 187

  Fly   222 GHSSFAFASFGFIAYYIGAKLHAFDSRGRGHTW---RLCIAVIPLFI---ALLVAVSRTCDYHHH 280
            |||||......|:|.|:.|:|          .|   ||....:..|:   ||.|..:|..||.||
Human   188 GHSSFGMYCMVFLALYVQARL----------CWKWARLLRPTVQFFLVAFALYVGYTRVSDYKHH 242

  Fly   281 WQDVTIGGLIG-----LFAGYIS 298
            |.||.:|.|.|     |...|||
Human   243 WSDVLVGLLQGALVAALTVCYIS 265

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG12746	NP_649551.4	PAP2_containing_1_like	104..302	CDD:239484	68/218 (31%)
PLPP2	NP_808211.1	PAP2_wunen	115..261	CDD:239479	51/163 (31%)