Protein Alignment CG12746 and PLPP5

DIOPT Version :10

• Sequence 1: NP_649551.4
• Gene: CG12746 / 40672
• FlyBaseID: FBgn0037341
• Length: 363
• Species: Drosophila melanogaster
• Sequence 2: XP_024303075.2
• Gene: PLPP5 / 84513
• HGNCID: 25026
• Length: 293
• Species: Homo sapiens
• Alignment Length: 275
• Identity: 112/275 - (40%)
• Similarity: 153/275 - (55%)
• Gaps: 43/275 - (15%)

  Fly    63 GNSNAKLSDAVDVVLRVLLVITFFKLETMTAFKREIHEEELWLYKN--------PRRPDIVRG-- 117
            |.:.|.::...:|.:|:.|...|...|.:..|:|.|..||:|||:|        |.:|..|||
Human     2 GKAAAAVAFGAEVGVRLALFAAFLVTELLPPFQRLIQPEEMWLYRNPYVEAEYFPTKPMFVRGER 66

  Fly   118 ------------GELLFW--------VIVAPF-LVTIAFYWYTRDRRDFRAASWAWTLALCMNGI 161
                        |.|..:        ..::|. |:.:|.:....|.||.|.|..|.:|||.:||:
Human    67 SSFLPPHDPASRGHLCVFHPETAFVIAFLSPLSLIFLAKFLKKADTRDSRQACLAASLALALNGV 131

  Fly   162 PTSVLKITVGRPRPDYFYRCFPDGVMVLNTTSNGVDTSILDFNCTGLPGDINEGRKSFPSGHSSF 226
            .|:.:|:.|||||||:||||||||:            :..|..|||....:||||||||||||||
Human   132 FTNTIKLIVGRPRPDFFYRCFPDGL------------AHSDLMCTGDKDVVNEGRKSFPSGHSSF 184

  Fly   227 AFASFGFIAYYIGAKLHAFDSRGRGHTWRLCIAVIPLFIALLVAVSRTCDYHHHWQDVTIGGLIG 291
            |||...|.::|:..|||.|..:|||.:||.|..:.||..|.::|:||||||.||||||.:|.:||
Human   185 AFAGLAFASFYLAGKLHCFTPQGRGKSWRFCAFLSPLLFAAVIALSRTCDYKHHWQDVLVGSMIG 249

  Fly   292 LFAGYISYTQYYPSI 306
            :...|:.|.||||.:
Human   250 MTFAYVCYRQYYPPL 264

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG12746	NP_649551.4	PAP2_containing_1_like	104..302	CDD:239484	96/228 (42%)
PLPP5	XP_024303075.2	PAP2_containing_1_like	43..260	CDD:239484	96/228 (42%)