DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG12746 and SGPP1

DIOPT Version :9

Sequence 1:	NP_649551.4	Gene:	CG12746 / 40672	FlyBaseID:	FBgn0037341	Length:	363	Species:	Drosophila melanogaster
Sequence 2:	NP_110418.1	Gene:	SGPP1 / 81537	HGNCID:	17720	Length:	441	Species:	Homo sapiens

Alignment Length:	162	Identity:	31/162 - (19%)
Similarity:	57/162 - (35%)	Gaps:	52/162 - (32%)

- Green bases have known domain annotations that are detailed below.

  Fly    38 RNELAMNTDSSSVQPEKREERSHRTGNSN--AKLSDAVDVVLRVLLVITFFKLETMTAFKREIHE 100
            ||.||.....:|.:......|:..||...  |::|:              :.|..:..|..|:..
Human    90 RNGLAAELGPASPRRAGALRRNSLTGEEGQLARVSN--------------WPLYCLFCFGTELGN 140

  Fly   101 E-------ELWLYK-NPRRPDIVRGGELLFWVIV-----------------APFLVTIAFYWYTR 140
            |       ..|::. :|    :|....::.||:|                 :|.:|.:..::.:.
Human   141 ELFYILFFPFWIWNLDP----LVGRRLVVIWVLVMYLGQCTKDIIRWPRPASPPVVKLEVFYNSE 201

  Fly   141 DRRDFRAASWAWTLALCMNGIPTSVLKITVGR 172
                   .|...|.|:....||.|::.:|.||
Human   202 -------YSMPSTHAMSGTAIPISMVLLTYGR 226

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG12746	NP_649551.4	PAP2_containing_1_like	104..302	CDD:239484	17/87 (20%)
SGPP1	NP_110418.1	Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	25..110		5/19 (26%)
		PAP2_SPPase1	126..275	CDD:239482	21/112 (19%)
		Phosphatase sequence motif I. /evidence=ECO:0000305	178..186		0/7 (0%)
		Phosphatase sequence motif II. /evidence=ECO:0000305	205..208		0/2 (0%)
		Phosphatase sequence motif III. /evidence=ECO:0000305	248..259
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0671
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	1	0.900