DRSC/TRiP Functional Genomics Resources

powered by:
logo

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits


Protein Alignment CG12746 and PLPPR2

DIOPT Version :9

Sequence 1:NP_649551.4 Gene:CG12746 / 40672 FlyBaseID:FBgn0037341 Length:363 Species:Drosophila melanogaster
Sequence 2:NP_001380821.1 Gene:PLPPR2 / 64748 HGNCID:29566 Length:452 Species:Homo sapiens


Alignment Length:195 Identity:48/195 - (24%)
Similarity:78/195 - (40%) Gaps:33/195 - (16%)


- Green bases have known domain annotations that are detailed below.


  Fly   167 KITVGRPRPDYFYRCFPD----GVMVLNTTSNGVDTSILDFN-CTGLPGDINEGRKSFPSGHSSF 226
            ::..|.|.|.:...|.|:    |.:..:....|.|..:.|.. |.|.|..:...|::||...::.
Human   148 QVVTGNPTPHFLSVCRPNYTALGCLPPSPDRPGPDRFVTDQGACAGSPSLVAAARRAFPCKDAAL 212

  Fly   227 AFASFGFIAYYIGAKLHAFDSRGRGHTWRLCIAVI-PLFIALLVAVSRTCDYHHHWQDVTIGGLI 290
            ...:..:.|.|:........||....:  ||:|:: |.|   ||.|.|..:|.:||.||..|.|.
Human   213 CAYAVTYTAMYVTLVFRVKGSRLVKPS--LCLALLCPAF---LVGVVRVAEYRNHWSDVLAGFLT 272

  Fly   291 GLFAGYISYTQYYPSIFC--------PDAGIPLVRW------PSREGSQYQRLSGKDDNGSRGPH 341
            |  |...::.     :.|        |.:|..|..|      |:.: |..::||...:.....||
Human   273 G--AAIATFL-----VTCVVHNFQSRPPSGRRLSPWEDLGQAPTMD-SPLEKLSVAQEPEVCRPH 329

  Fly   342  341
            Human   330  329

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
CG12746NP_649551.4 PAP2_containing_1_like 104..302 CDD:239484 37/140 (26%)
PLPPR2NP_001380821.1 PAP2_wunen 125..281 CDD:239479 37/144 (26%)


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 1 0.930 - - C165144618
Domainoid 00.000 Not matched by this tool.
eggNOG 1 0.900 - - E1_COG0671
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 1 1.010 - - D1621899at2759
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
User_Submission 00.000 Not matched by this tool.
43.750

Return to query results.
Submit another query.