Protein Alignment CG12746 and PLPPR1

DIOPT Version :10

• Sequence 1: NP_649551.4
• Gene: CG12746 / 40672
• FlyBaseID: FBgn0037341
• Length: 363
• Species: Drosophila melanogaster
• Sequence 2: NP_060223.2
• Gene: PLPPR1 / 54886
• HGNCID: 25993
• Length: 325
• Species: Homo sapiens
• Alignment Length: 264
• Identity: 66/264 - (25%)
• Similarity: 99/264 - (37%)
• Gaps: 58/264 - (21%)

  Fly    89 ETMTAFKREIHEEELWLYKNPRRPDIVRGGELLFWVIVAPFLVTIAFYWYTRDRRDFRAASWAWT 153
            |::.|.::.|...|. .|.||....|:|            |....||..:..|
Human   100 ESLIAQEKTILTGEC-CYLNPLLRRIIR------------FTGVFAFGLFATD------------ 139

  Fly   154 LALCMNGIPTSVLKITVGRPRPDYFYRCFPDGVMVLNTTSNGVDTSILDFN----CTGLPGDINE 214
                   |..:..::..|...|.:...|.|      |.||..........|    |||....|.:
Human   140 -------IFVNAGQVVTGHLTPYFLTVCKP------NYTSADCQAHHQFINNGNICTGDLEVIEK 191

  Fly   215 GRKSFPSGHSSFAFASFGFIAYYIGAKLHAFDSRGRGHTWRLCIAVIPLFIALLVAVSRTCDYHH 279
            .|:||||.|::.:..|..:...||.:.:....||.....  ||:..  |..|.|..::|..:|.:
Human   192 ARRSFPSKHAALSIYSALYATMYITSTIKTKSSRLAKPV--LCLGT--LCTAFLTGLNRVSEYRN 252

  Fly   280 HWQDVTIGGLIG----LFAGY-----ISYTQYYPSIFCPD--AGIPLVRWPSREGSQYQRLSGKD 333
            |..||..|.::|    ||.|.     ...||..||...|:  .|:||:.:|..| |..:.||.::
Human   253 HCSDVIAGFILGTAVALFLGMCVVHNFKGTQGSPSKPKPEDPRGVPLMAFPRIE-SPLETLSAQN 316

  Fly   334 DNGS 337
            .:.|
Human   317 HSAS 320

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG12746	NP_649551.4	PAP2_containing_1_like	104..302	CDD:239484	49/210 (23%)
PLPPR1	NP_060223.2	PAP2_wunen	123..272	CDD:239479	44/189 (23%)