DRSC/TRiP Functional Genomics Resources

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Protein Alignment CG12746 and Plpp2

DIOPT Version :9

Sequence 1:NP_649551.4 Gene:CG12746 / 40672 FlyBaseID:FBgn0037341 Length:363 Species:Drosophila melanogaster
Sequence 2:NP_056632.2 Gene:Plpp2 / 50784 MGIID:1354945 Length:276 Species:Mus musculus


Alignment Length:282 Identity:81/282 - (28%)
Similarity:123/282 - (43%) Gaps:56/282 - (19%)


- Green bases have known domain annotations that are detailed below.


  Fly    73 VDVVLRVLLVIT----FFKLETMTA-FKREIH--EEELWLYKNPRRPDIVRGGELLFWVIVAPFL 130
            |.|:|.||.|:.    |..|..:.| :||..:  ::.:   :.|.|||.:..| |:..||:...:
Mouse     6 VFVLLDVLCVLVASLPFIILTLVNAPYKRGFYCGDDSI---RYPYRPDTITHG-LMAGVIITATV 66

  Fly   131 VTI----AFYWYTRDR-------RDFRAASW----AWTLALCMNGIPTSVLKITVGRPRPDYFYR 180
            :.:    |:..|| ||       .::.||.:    .:.....::...|.:.|..:||.||.:...
Mouse    67 ILVSLGEAYLVYT-DRLYSRSNFNNYVAAIYKVLGTFLFGAAVSQSLTDLAKYMIGRLRPSFLAV 130

  Fly   181 CFPDGVMVLNTTSNGVDTSILDFNCTGLPGDINEGRKSFPSGHSSFAFASFGFIAYYIGAKLHAF 245
            |.||...|  ..|..|...:    |.|.|.::.|.|.||.||||||......|:|.|:.|:|   
Mouse   131 CDPDWSQV--NCSGYVQLEV----CRGSPANVTEARLSFYSGHSSFGMYCMLFLALYVQARL--- 186

  Fly   246 DSRGRGHTW---RLCIAVIPLFI---ALLVAVSRTCDYHHHWQDVTIGGLIG-----LFAGYIS- 298
                   .|   ||....:..|:   |:.|..:|..|:.|||.||.:|.|.|     |...|:| 
Mouse   187 -------CWKWARLLRPTVQFFLVAFAIYVGYTRVSDHKHHWSDVLVGLLQGALVACLTVRYVSD 244

  Fly   299 YTQYYPSIFCPDAGIPLVRWPS 320
            :.:..|...|.:..:| .|.||
Mouse   245 FFKSRPPQPCQEDEVP-ERKPS 265

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
CG12746NP_649551.4 PAP2_containing_1_like 104..302 CDD:239484 64/224 (29%)
Plpp2NP_056632.2 PAP2_wunen 94..239 CDD:239479 48/160 (30%)
Phosphatase sequence motif I. /evidence=ECO:0000250|UniProtKB:O34349 117..125 3/7 (43%)
Phosphatase sequence motif II. /evidence=ECO:0000250|UniProtKB:O34349 164..167 1/2 (50%)
Phosphatase sequence motif III. /evidence=ECO:0000250|UniProtKB:O34349 212..223 5/10 (50%)
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 251..276 5/16 (31%)


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 1 0.930 - - C167834809
Domainoid 00.000 Not matched by this tool.
eggNOG 1 0.900 - - E1_COG0671
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 1 1.010 - - D1621899at2759
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
43.750

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