DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG12746 and plpp5

DIOPT Version :9

Sequence 1:	NP_649551.4	Gene:	CG12746 / 40672	FlyBaseID:	FBgn0037341	Length:	363	Species:	Drosophila melanogaster
Sequence 2:	XP_005155353.1	Gene:	plpp5 / 431758	ZFINID:	ZDB-GENE-040704-54	Length:	358	Species:	Danio rerio

Alignment Length:	258	Identity:	118/258 - (45%)
Similarity:	155/258 - (60%)	Gaps:	18/258 - (6%)

- Green bases have known domain annotations that are detailed below.

  Fly    74 DVVLRVLLVITFFKLETMTAFKREIHEEELWLYK-NPRRPDIVRGGELLFWVIVAPFLVTIAFYW 137
            :|.:|:||:..|...|.:..|.|||..||||||| :|.:.|.|....:....:..|.||...|.:
Zfish   104 EVAVRLLLLGLFLVTEELPPFSREIQPEELWLYKFHPVKKDRVPTRFMFAIALFTPLLVIFLFAF 168

  Fly   138 YTR-DRRDFRAASWAWTLALCMNGIPTSVLKITVGRPRPDYFYRCFPDGVMVLNTTSNGVDTSIL 201
            ..: .:.|.:.||.|.||.|.:||:.|:.:|:.|||||||:||||||||.|  |.
Zfish   169 LKQGGKGDLKEASLAVTLTLVLNGVFTNAVKLAVGRPRPDFFYRCFPDGQM--NP---------- 221

  Fly   202 DFNCTGLPGDINEGRKSFPSGHSSFAFASFGFIAYYIGAKLHAFDSRGRGHTWRLCIAVIPLFIA 266
            :.:|:|.|..:.||||||||||||||||..||.|.|:..|||.|.:.|:|..||||..:.||..|
Zfish   222 ELHCSGDPDVVMEGRKSFPSGHSSFAFAGLGFTALYVAGKLHCFSTAGQGKAWRLCAFLTPLLFA 286

  Fly   267 LLVAVSRTCDYHHHWQDVTIGGLIGLFAGYISYTQYYPSIFCPDAGIPL----VRWPSREGSQ 325
            :|:|:||||||.||||||.:|.|:||...|:.|.|:||::..||...||    ...|:.|..|
Zfish   287 ILIALSRTCDYKHHWQDVLVGSLLGLVFSYLCYRQHYPALNEPDCHRPLRMRETALPAAERKQ 349

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG12746	NP_649551.4	PAP2_containing_1_like	104..302	CDD:239484	95/199 (48%)
plpp5	XP_005155353.1	PAP2_containing_1_like	134..322	CDD:239484	95/199 (48%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C170577886
Domainoid	1	1.000	181	1.000	Domainoid score	I3429
eggNOG	1	0.900	-	-		E1_COG0671
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H100569
Inparanoid	1	1.050	222	1.000	Inparanoid score	I3511
OMA	1	1.010	-	-		QHG50067
OrthoDB	1	1.010	-	-		D1621899at2759
OrthoFinder	1	1.000	-	-		FOG0001532
OrthoInspector	1	1.000	-	-		otm25653
orthoMCL	1	0.900	-	-		OOG6_100228
Panther	1	1.100	-	-	O	PTHR10165
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X622
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	14	13.810