DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG12746 and SPBC409.18

DIOPT Version :9

Sequence 1:	NP_649551.4	Gene:	CG12746 / 40672	FlyBaseID:	FBgn0037341	Length:	363	Species:	Drosophila melanogaster
Sequence 2:	NP_595468.1	Gene:	SPBC409.18 / 2541078	PomBaseID:	SPBC409.18	Length:	279	Species:	Schizosaccharomyces pombe

Alignment Length:	265	Identity:	77/265 - (29%)
Similarity:	124/265 - (46%)	Gaps:	58/265 - (21%)

- Green bases have known domain annotations that are detailed below.

  Fly    80 LLVITF---FKLETMT-AFKREIHEE--------------ELWLYKNPRRPDIVRGGELLFWVIV 126
            :|::.|   |.||.:| :....:||:              .|.||...:    :|...||||..:
pombe    33 VLMLPFTRQFSLEDITISHPFALHEQVPTKYLGIICVFFPALVLYGFGK----LRNNSLLFWKSL 93

  Fly   127 APFLVTIAFYWYTRDRRDFRAASWAWTLALCMNGIPTSVLKITVGRPRPDYFYRCFPDGVMVLNT 191
            ...|                     ::..:|  |:..|:||..|||||||:..||.|     ..:
pombe    94 MGLL---------------------YSTMVC--GLCVSLLKNAVGRPRPDFLARCQP-----FES 130

  Fly   192 TSNGVDTSILDFNCTGLPGD---INEGRKSFPSGHSSFAFASFGFIAYYIGAKLHAFDSRGRGHT 253
            |..   |.::|.....:|..   :.:|.:||||||:||:||..||:|.::..:|..|  |.:..:
pombe   131 TPK---TGLVDVLSCSVPWSDKVLQDGFRSFPSGHTSFSFAGLGFLAIFLAGQLKMF--RNKTSS 190

  Fly   254 WRLCIAVIPLFIALLVAVSRTCDYHHHWQDVTIGGLIGLFAGYISYTQYYPSIFCPDAGIPLVRW 318
            |::.:.::||.||..:.:||:.||.||.:|:.:|.|.|....|:.|.|.:|.:...:|.|..|:.
pombe   191 WKVVVPLVPLSIASWIGLSRSQDYRHHKEDIAVGALFGFAIAYVVYRQLFPPLDHHNADILYVQA 255

  Fly   319 PSREG 323
            ...||
pombe   256 ELDEG 260

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG12746	NP_649551.4	PAP2_containing_1_like	104..302	CDD:239484	61/200 (31%)
SPBC409.18	NP_595468.1	PgpB	7..247	CDD:223743	72/250 (29%)
SPBC409.18	NP_595468.1	PAP2_containing_1_like	47..238	CDD:239484	65/227 (29%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	1	1.000	103	1.000	Domainoid score	I1744
eggNOG	1	0.900	-	-		E1_COG0671
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0001532
OrthoInspector	1	1.000	-	-		oto101897
orthoMCL	1	0.900	-	-		OOG6_100228
Panther	1	1.100	-	-	O	PTHR10165
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R3374
SonicParanoid	1	1.000	-	-		X622
TreeFam	1	0.960	-	-
	11	10.800