Protein Alignment CG12746 and Plpp2

DIOPT Version :10

• Sequence 1: NP_649551.4
• Gene: CG12746 / 40672
• FlyBaseID: FBgn0037341
• Length: 363
• Species: Drosophila melanogaster
• Sequence 2: NP_640345.1
• Gene: Plpp2 / 246115
• RGDID: 628893
• Length: 276
• Species: Rattus norvegicus
• Alignment Length: 262
• Identity: 78/262 - (29%)
• Similarity: 112/262 - (42%)
• Gaps: 49/262 - (18%)

  Fly    73 VDVVLRVLLVIT----FFKLETMTA-FKREIH--EEELWLYKNPRRPDIVRGGELLFWVIVAPFL 130
            |.|:|.||.|:.    |..|..:.| :||..:  ::.:   :.|.|||.:..| |:..||:...:
  Rat     6 VFVLLDVLCVLVASLPFIILTLVNAPYKRGFYCGDDSI---RYPYRPDTITHG-LMAGVIITATV 66

  Fly   131 VTI----AFYWYT---RDRRDFR---AASW----AWTLALCMNGIPTSVLKITVGRPRPDYFYRC 181
            |.:    |:..||   ..|.||.   ||.:    .:.....::...|.:.|..:||.||.:...|
  Rat    67 VLVSSGEAYLVYTDRLYSRSDFNNYVAAIYKVLGTFLFGAAVSQSLTDLAKYMIGRLRPSFLAVC 131

  Fly   182 FPDGVMVLNTTSNGVDTSILDFNCTGLPGDINEGRKSFPSGHSSFAFASFGFIAYYIGAKLHAFD 246
            .||...|  ..|..|...:    |.|.|.::.|.|.||.||||||......|:|.|:.|:|
  Rat   132 DPDWSRV--NCSGYVQVEV----CRGSPANVTEARLSFYSGHSSFGMYCMLFLALYVQARL---- 186

  Fly   247 SRGRGHTW---RLCIAVIPLFI---ALLVAVSRTCDYHHHWQDVTIGGLIGLFAGYISYTQYYPS 305
                  .|   ||....:..|:   |:.|..:|..|..|||.||.:|.|.|.....:  |..|.|
  Rat   187 ------CWKWARLLRPTVQFFLVAFAIYVGYTRVSDNKHHWSDVLVGLLQGALVACL--TVCYVS 243

  Fly   306 IF 307
            .|
  Rat   244 DF 245

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG12746	NP_649551.4	PAP2_containing_1_like	104..302	CDD:239484	64/217 (29%)
Plpp2	NP_640345.1	PAP2_wunen	94..239	CDD:239479	47/162 (29%)
		Phosphatase sequence motif I. /evidence=ECO:0000250|UniProtKB:O34349	117..125		3/7 (43%)
		Phosphatase sequence motif II. /evidence=ECO:0000250|UniProtKB:O34349	164..167		1/2 (50%)
		Phosphatase sequence motif III. /evidence=ECO:0000250|UniProtKB:O34349	212..223		5/10 (50%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	252..276