DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG12746 and Plppr4

DIOPT Version :9

Sequence 1:	NP_649551.4	Gene:	CG12746 / 40672	FlyBaseID:	FBgn0037341	Length:	363	Species:	Drosophila melanogaster
Sequence 2:	NP_808332.3	Gene:	Plppr4 / 229791	MGIID:	106530	Length:	766	Species:	Mus musculus

Alignment Length:	217	Identity:	56/217 - (25%)
Similarity:	91/217 - (41%)	Gaps:	55/217 - (25%)

- Green bases have known domain annotations that are detailed below.

  Fly   156 LCMNGIPTSVLKITVGRPRPDYFYRCFPDGVMVLNTTSNGV----DTSILDFNCTGLPGD---IN 213
            ||...:.|.:::::.|...|.:...|.|      |.||..|    ::.|::..|:|  .|   ||
Mouse   187 LCSTALITDIIQLSTGYQAPYFLTVCKP------NYTSLNVSCKENSYIVEDICSG--SDLTVIN 243

  Fly   214 EGRKSFPSGHSSFAFASFGFIAYYIGAKLHAFDSRGRGHTWRLCIAVIPLFI------ALLVAVS 272
            .|||||||.|::.|..:..:::.|..:.|  .||..         .:.||.:      .::..::
Mouse   244 SGRKSFPSQHATLAAFAAVYVSMYFNSTL--TDSSK---------LLKPLLVFTFIICGIICGLT 297

  Fly   273 RTCDYHHHWQDV----TIGGLIGLFAGYISYTQYYPSIFCPDAGI----------PLVRWPSREG 323
            |...|.:|..||    .|||.|.|:.|..:...:.||   .|:.:          .|.:.|||.
Mouse   298 RITQYKNHPVDVYCGFLIGGGIALYLGLYAVGNFLPS---EDSMLQHRDALRSLTDLNQDPSRV- 358

  Fly   324 SQYQRLSGKDDNGSRGPHHLDG 345
                 ||.|:.:...|..|.:|
Mouse   359 -----LSAKNGSSGDGIAHTEG 375

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG12746	NP_649551.4	PAP2_containing_1_like	104..302	CDD:239484	43/162 (27%)
Plppr4	NP_808332.3	PAP2_wunen	175..324	CDD:239479	42/155 (27%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	454..494
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	634..654
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	672..701
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	742..766
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C167834762
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0671
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1621899at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	4	3.750